Rini James, Ochoa Juan
Behavioral Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.
Department of Neurology, University of South Alabama Medical Center, Mobile, AL, USA.
Neurol Clin Neurosci. 2020 Jul;8(4):177-182. doi: 10.1111/ncn3.12375. Epub 2020 Feb 21.
As ictal semiology is increasingly understood to arise from epileptogenic networks, high-frequency oscillation propagation patterns are helping elucidate networks relevant for surgical planning. Musical automatisms, a well-documented but very rare phenomenon of epilepsy, have yet to be examined as a manifestation of high-frequency propagation in the public literature. In our current study, we report a rare case intractable epilepsy with ictal humming whose epileptogenic zone was associated with the non-dominant left anterior medial temporal region. Mapping our case's ictal semiology and high-frequency propagation pattern both facilitated treatment and further supports prior observations that the rare phenomena of musical automatisms localize to a non-dominant frontal-temporal network rather than a specific cortical territory.
由于发作期症状学越来越被认为源自致痫网络，高频振荡传播模式有助于阐明与手术规划相关的网络。音乐自动症是一种有充分记录但非常罕见的癫痫现象，在公开文献中尚未被作为高频传播的一种表现进行研究。在我们当前的研究中，我们报告了一例罕见的顽固性癫痫病例，其发作期有哼唱，致痫区与非优势侧左前内侧颞叶区域相关。描绘该病例的发作期症状学和高频传播模式既有助于治疗，也进一步支持了先前的观察结果，即音乐自动症这种罕见现象定位于非优势侧额颞网络而非特定的皮质区域。
