Villodre Celia, Carbonell Silvia, Espinosa Javier, Bravo Jose Antonio, Zubiaga Lorea, Rojas Silvia, Abad Rafael, Campos Luis, Alcázar Cándido, Franco Mariano, Estrada Jose Luis, Zapater Pedro, Mena Luis, Lluís Félix
Servicio de Cirugía General y del Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, España.
Cir Esp. 2012 Jan;90(1):24-32. doi: 10.1016/j.ciresp.2011.06.004. Epub 2011 Sep 3.
The aim of the present study was to assess the predictive capacity of the POSSUM system in a Spanish university hospital, and to determine its behaviour in elective gastrointestinal surgery and compare it with emergency gastrointestinal surgery (operation < 24 hours).
A total of 1,000 surgical episodes corresponding to 909 patients who required hospital admission, operated on under general or loco-regional anaesthesia, either in the elective (n= 547 episodes) or the emergency setting (n= 453), were included in the study.
The overall morbidity was 31.9% (32.8% in elective surgery; 30.7% in emergency surgery). The discriminatory capacity of the POSSUM scale, evaluated using receiver operating characteristic (ROC) curves, was higher for the Portsmouth variant of mortality (Area Under the Curve [AUC] = 0,92) than for morbidity (AUC= 0,74). The goodness of fit between the expected values using the POSSUM scale and those observed was reduced for morbidity (Hosmer-Lemeshow [H-L] = 164.1; p< 0.05). The POSSUM scale predicted a higher number of deaths than those observed, although the Portsmouth variant was better at predicting mortality. The goodness of fit for morbidity was better for elective gastrointestinal surgery (H-L= 27.7) than emergency gastrointestinal surgery (H-L= 177.3). The logistic regression analysis identified (besides the estimated risk using the POSSUM scale itself), surgical complexity, surgery type (elective, emergency), and age of patient, as significant predictive factors of morbidity and mortality.
In a Spanish university hospital, the POSSUM system adequately predicts morbidity risk in elective gastrointestinal surgery, and over-estimates morbidity risk in emergency gastrointestinal surgery.
本研究旨在评估POSSUM系统在一家西班牙大学医院中的预测能力,并确定其在择期胃肠手术中的表现,并与急诊胃肠手术(手术时间<24小时)进行比较。
本研究纳入了1000例手术病例,这些病例对应909例需要住院治疗的患者,他们在全身麻醉或局部区域麻醉下接受手术,手术类型包括择期手术(n = 547例)或急诊手术(n = 453例)。
总体发病率为31.9%(择期手术为32.8%;急诊手术为30.7%)。使用受试者工作特征(ROC)曲线评估,POSSUM量表对朴茨茅斯死亡率变体的鉴别能力高于发病率(曲线下面积[AUC]=0.92)(AUC = 0.74)。使用POSSUM量表得出的预期值与观察值之间的拟合优度在发病率方面降低(Hosmer-Lemeshow[H-L]=164.1;p<0.05)。POSSUM量表预测的死亡人数高于观察到的死亡人数,尽管朴茨茅斯变体在预测死亡率方面表现更好。择期胃肠手术的发病率拟合优度(H-L = 27.7)优于急诊胃肠手术(H-L = 177.3)。逻辑回归分析确定(除了使用POSSUM量表本身估计的风险外),手术复杂性、手术类型(择期、急诊)和患者年龄是发病率和死亡率的重要预测因素。
在一家西班牙大学医院中,POSSUM系统能够充分预测择期胃肠手术的发病风险,但高估了急诊胃肠手术的发病风险。