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抗生素锁治疗革兰阴性杆菌所致长期导管相关性菌血症的疗效：一项前瞻性观察研究。

Effectiveness of antibiotic-lock therapy for long-term catheter-related bacteremia due to Gram-negative bacilli: a prospective observational study.

机构信息

Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Medicine Department, Spain.

出版信息

Clin Infect Dis. 2011 Nov;53(9):e129-32. doi: 10.1093/cid/cir551. Epub 2011 Sep 2.

DOI:10.1093/cid/cir551
PMID:21890750
Abstract

A prospective observational study evaluated the effectiveness of combining antibiotic-lock therapy and systemic antibiotics for Gram-negative bacilli long-term catheter-related bacteremia. In 46 uncomplicated episodes, the most frequently isolated microorganisms were Pseudomonas aeruginosa (15), Enterobacter cloacae (12), Escherichia coli (10), and Klebsiella spp. (8). Cure was achieved in 95% of cases.

摘要

一项前瞻性观察研究评估了抗生素锁治疗联合全身抗生素治疗革兰氏阴性杆菌长期导管相关性菌血症的疗效。在 46 例非复杂性感染中，最常分离到的微生物是铜绿假单胞菌（15 例）、阴沟肠杆菌（12 例）、大肠埃希菌（10 例）和克雷伯菌属（8 例）。95%的病例治愈。

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