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巩膜瓣和巩膜造口的形状和尺寸是否影响小梁切除术的房水流出?一种有限元模拟方法。

Do shapes and dimensions of scleral flap and sclerostomy influence aqueous outflow in trabeculectomy? A finite element simulation approach.

机构信息

Department of Mechanical Engineering, National University of Singapore, Singapore.

出版信息

Br J Ophthalmol. 2012 Mar;96(3):432-7. doi: 10.1136/bjophthalmol-2011-300228. Epub 2011 Sep 2.

Abstract

BACKGROUND/AIM: This study aimed to provide an objective assessment of the effects on the aqueous outflow rate of various geometries of the scleral flap and sclerostomy created in trabeculectomy.

METHOD

Computer-based models and simulations of this surgical procedure were used to investigate the relative effects of various shapes and dimensions of scleral flap and sclerostomy on the aqueous outflow.

RESULT

In these computer simulations, increasing scleral flap size was found to be associated with an increase of 48.55% in aqueous egress. In addition, a square scleral flap increased the aqueous drainage by 36.26% compared with a triangular flap of equivalent flap area. Surprisingly, our simulation results showed that a smaller semicircular sclerostomy improved aqueous drainage by up to 33.00%, while a semicircular sclerostomy, compared with a circular sclerostomy, led to a further 6.16% increase in aqueous outflow. Decreasing flap thickness beyond half-thickness caused an additional increase in aqueous outflow. However, clinically the flap should not be thinner than half the thickness of the sclera as this may result in hypotony.

CONCLUSION

These simulations indicate that the optimal flow rate through operation site will be achieved in trabeculectomy using a square scleral flap with a large flap-to-sclerostomy ratio.

摘要

背景/目的:本研究旨在客观评估在小梁切除术中小梁瓣和巩膜造口的各种几何形状对房水流出率的影响。

方法

使用基于计算机的模型和模拟来研究不同形状和尺寸的小梁瓣和巩膜造口对房水流出的相对影响。

结果

在这些计算机模拟中,发现增大小梁瓣的尺寸与房水流出增加 48.55%相关。此外,与具有相同瓣面积的三角形瓣相比,方形小梁瓣增加了 36.26%的房水引流。令人惊讶的是,我们的模拟结果表明,较小的半圆形巩膜造口可将房水引流提高多达 33.00%,而与圆形巩膜造口相比,半圆形巩膜造口可使房水流出进一步增加 6.16%。瓣厚度减小超过半厚度会导致房水流出增加。然而,临床上瓣不应比巩膜的一半厚度薄,因为这可能导致低眼压。

结论

这些模拟表明,在小梁切除术中使用具有较大瓣-巩膜造口比的方形小梁瓣可实现最佳的手术部位流量。

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