Mally Rahul, Sharma Mayur, Khan Shadma, Velho Vernon
Department of Neurosurgery, Sir J. J. Group of Hospitals, Grant Medical College, Mumbai, Maharashtra, India.
Asian Spine J. 2011 Sep;5(3):192-5. doi: 10.4184/asj.2011.5.3.192. Epub 2011 Aug 12.
We present a case of 24-year-old male presented with low back pain radiating to the left lower limb, tingling numbness and weakness of 6 months duration. Magnetic resonance imaging scan with contrast reveals an extradural mass at lumbosacral region. Patient was operated with laminectomy and complete excision of the lesion was done. Patient's radicular pain relieved following the surgery and weakness also improved. Histopathology was suggestive of non-Hodgkin's lymphoma. Patient received chemotherapy which was followed by radiotherapy. Primary Non-Hodgkin's lymphoma of the lumbosacral spinal epidural tissue is an uncommon lesion. Lymphoma involves the central nervous system in 5-11% of cases either at presentation of the disease or during its course. The spinal epidural tissue is involved primarily in 0.1-3.3% of cases with spinal cord compression being the commonest presentation. Excision of the lesion followed by chemotherapy and radiotherapy is required to achieve cure.
我们报告一例24岁男性，出现下背部疼痛并向左下肢放射，伴有刺痛、麻木和无力症状，持续6个月。增强磁共振成像扫描显示腰骶部硬膜外肿块。患者接受了椎板切除术，病变被完整切除。术后患者的神经根性疼痛缓解，无力症状也有所改善。组织病理学提示为非霍奇金淋巴瘤。患者接受了化疗，随后进行了放疗。腰骶部脊髓硬膜外组织原发性非霍奇金淋巴瘤是一种罕见病变。在5%-11%的病例中，淋巴瘤在疾病表现期或病程中累及中枢神经系统。脊髓硬膜外组织受累主要见于0.1%-3.3%的病例，脊髓压迫是最常见的表现。为实现治愈，需要切除病变，随后进行化疗和放疗。
