Department of General, Visceral and Vascular Surgery, University of Jena, Erlanger Allee 101, 07740 Jena, Germany.
Gastric Cancer. 2012 Apr;15(2):131-6. doi: 10.1007/s10120-011-0080-y. Epub 2011 Sep 3.
Although up to 9% of patients with gastric cancer develop liver metastases, liver resection is rarely performed because of co-existing non-curative factors. Furthermore, the benefit of liver resection is still controversially discussed. Our goal was to investigate the outcome of patients who underwent liver resection or radiofrequency ablation (RFA) for hepatic metastasized gastric cancer.
Retrospectively collected data from a prospectively maintained database were analyzed from 15 patients who underwent liver resection or RFA for liver metastases from gastric cancer.
Overall 5-year survival and median survival were 27% and 48 months for resected/RFA patients. The peri-operative complication rate was low. One patient has been tumor-free for 90 months now.
Liver resection in patients with hepatic metastasized gastric cancer is beneficial and safe if an R0 situation can be achieved. RFA might be a useful alternative in those patients where surgery is not feasible.
尽管高达 9%的胃癌患者会发展为肝转移，但由于存在不可治愈的因素，肝切除术很少进行。此外，肝切除术的益处仍存在争议。我们的目的是研究接受肝切除术或射频消融术（RFA）治疗胃转移性肝癌患者的结果。
从前瞻性维护的数据库中回顾性收集了 15 例接受肝切除术或 RFA 治疗胃转移性肝癌的患者数据。
总的 5 年生存率和中位生存时间分别为接受切除/RFA 治疗患者的 27%和 48 个月。围手术期并发症发生率较低。一名患者现在已无肿瘤 90 个月。
如果能够达到 R0 状态，肝切除术对肝转移性胃癌患者是有益且安全的。对于那些手术不可行的患者，RFA 可能是一种有用的替代方法。
