Sáenz-Francés F, García-Catalán R, Jerez-Fidalgo M, Fernández-Vidal A, Martínez-de-la-Casa J M, Méndez-Hernández C, Santos-Bueso E, Reche-Frutos J, García-Sánchez J, García-Feijoo J
Hospital Clínico Universitario San Carlos, Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense, Madrid, España.
Arch Soc Esp Oftalmol. 2011 Sep;86(9):287-91. doi: 10.1016/j.oftal.2011.04.012. Epub 2011 Jul 19.
To compare intraocular pressure (IOP) measurements made by Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT).
IOPs were measured by GAT and DCT in 63 eyes of 63 healthy subjects. A comparison was made by intraclass correlation coefficient. Passing-Bablok plot was constructed to establish the existence of systematic and/or proportional biases. Multivariate regression analysis was used to examine whether the measurements of both instruments were affected by the power of the steepest and flattest corneal axes, their orientation, age or central corneal thickness (CCT).
The intra-class correlations (ICCs) were 0.57 (95% confidence interval (95% CI): 0.29-0.74). Mean differences were 1.68 (DCT minus GAT) (95% CI: 0.92-2.44). Passing-Bablok analysis (X=DCT, Y=GAT) revealed a systematic bias (A=-14.35, 95% CI: -24.51-[-9.14]) and a proportional bias (B=1.74, 95% CI: 1.43-2.26). Multivariate regression analysis revealed that the DCT was independent of the corneal characteristics analysed while GAT was biased by CCT (B=0.042, 95% CI: 0.002-0.082).
While GAT was biased by corneal CCT; DCT readings were independent of corneal morphometry.
比较Goldmann压平眼压计(GAT)和动态轮廓眼压计(DCT)所测眼压(IOP)。
对63名健康受试者的63只眼分别用GAT和DCT测量眼压。采用组内相关系数进行比较。绘制Passing-Bablok图以确定是否存在系统偏差和/或比例偏差。采用多元回归分析来检验两种仪器的测量值是否受最陡和最平角膜轴的屈光度、其方向、年龄或中央角膜厚度(CCT)的影响。
组内相关系数(ICC)为0.57(95%置信区间[95%CI]:0.29 - 0.74)。平均差值为1.68(DCT减去GAT)(95%CI:0.92 - 2.44)。Passing-Bablok分析(X = DCT,Y = GAT)显示存在系统偏差(A = -14.35,95%CI:-24.51 - [-9.14])和比例偏差(B = 1.74,95%CI:1.43 - 2.26)。多元回归分析显示,DCT与所分析的角膜特征无关,而GAT受CCT影响(B = 0.042,95%CI:0.002 - 0.082)。
GAT受角膜CCT影响,而DCT读数与角膜形态测量无关。