Salvetat Maria L, Zeppieri Marco, Tosoni Claudia, Brusini Paolo
Department of Ophthalmology, Santa Maria della Misericordia Hospital, Udine, Italy.
Acta Ophthalmol Scand. 2007 May;85(3):272-9. doi: 10.1111/j.1600-0420.2006.00834.x.
To compare intraocular pressure (IOP) measurements taken with Pascal dynamic contour tonometry (DCT), the TonoPen and the Goldmann applanation tonometry (GAT). The influence of central corneal thickness (CCT) on IOP measurements taken with Pascal DCT and the TonoPen was evaluated.
One eye in each of 101 consecutive patients with primary open-angle glaucoma (POAG) underwent ultrasonic CCT measurement and IOP evaluation with GAT, Pascal DCT and the TonoPen in random order. The agreement between results from Pascal DCT and the TonoPen and those of GAT was assessed using the Bland-Altman method. The deviation of Pascal DCT and TonoPen readings from GAT values, corrected for CCT, was calculated and correlated to CCT using a linear regression model.
The mean of the differences in IOP measurements was 3.2 +/- 2.4 mmHg for Pascal DCT minus GAT readings and 0.5 +/- 4.5 mmHg for TonoPen minus GAT readings. The 95% confidence interval of differences in IOP measurements was higher between TonoPen and GAT readings (- 6 to 7 mmHg) than between Pascal and GAT readings (0.1-6.8 mmHg). Pascal DCT significantly overestimated IOP compared with GAT, especially for higher IOP readings. Bland-Altman scatterplots showed reasonable inter-method agreement between Pascal DCT and GAT measurements, and poor agreement between TonoPen and GAT measurements. The deviations of Pascal DCT and TonoPen readings from the corrected GAT values were both highly correlated with CCT values (linear regression analysis, p < 0.0001). The mean change in measured IOP for a 10-microm increase in CCT was 0.48 mmHg for Pascal DCT and 0.74 mmHg for the TonoPen.
Agreement with GAT measurements was higher for Pascal DCT than for TonoPen readings; however, Pascal DCT significantly overestimated IOP values compared with GAT. Measurements of IOP obtained with both Pascal DCT and the TonoPen appeared to be influenced by CCT, and this influence appeared to be greater for the latter.
比较使用帕斯卡动态轮廓眼压计（DCT）、托诺笔眼压计和戈德曼压平眼压计（GAT）测量眼压的结果。评估中央角膜厚度（CCT）对使用帕斯卡DCT和托诺笔眼压计测量眼压的影响。
对101例连续的原发性开角型青光眼（POAG）患者的单眼进行超声CCT测量，并随机使用GAT、帕斯卡DCT和托诺笔眼压计进行眼压评估。使用Bland-Altman方法评估帕斯卡DCT和托诺笔眼压计的测量结果与GAT测量结果之间的一致性。计算经CCT校正后帕斯卡DCT和托诺笔眼压计读数与GAT值的偏差，并使用线性回归模型将其与CCT进行相关性分析。
帕斯卡DCT减去GAT读数的眼压测量差异平均值为3.2±2.4 mmHg，托诺笔减去GAT读数的眼压测量差异平均值为0.5±4.5 mmHg。托诺笔与GAT读数之间眼压测量差异的95%置信区间（-6至7 mmHg）高于帕斯卡与GAT读数之间的差异（0.1 - 6.8 mmHg）。与GAT相比，帕斯卡DCT显著高估了眼压，尤其是对于较高的眼压读数。Bland-Altman散点图显示帕斯卡DCT与GAT测量之间的方法间一致性合理，而托诺笔与GAT测量之间的一致性较差。经校正的GAT值后，帕斯卡DCT和托诺笔眼压计读数的偏差均与CCT值高度相关（线性回归分析，p < 0.0001）。CCT每增加10微米，帕斯卡DCT测量的眼压平均变化为0.48 mmHg，托诺笔为0.74 mmHg。
帕斯卡DCT与GAT测量结果的一致性高于托诺笔眼压计读数；然而，与GAT相比，帕斯卡DCT显著高估了眼压值。使用帕斯卡DCT和托诺笔眼压计测量的眼压似乎都受CCT影响，且后者受影响更大。
