Halkiadakis Ioannis, Patsea Eleni, Chatzimichali Katerina, Skouriotis Sotiris, Chalkidou Sonia, Amariotakis Georgios, Papakonstadinou Dimitrios, Theodossiadis George, Amariotakis Apostolos, Georgopoulos Gerasimos
Ophthalmiatrion Athinon (Athens Eye Hospital), Athens, Greece.
Acta Ophthalmol. 2009 May;87(3):323-8. doi: 10.1111/j.1755-3768.2008.01239.x. Epub 2008 Jul 9.
To compare intraocular pressure (IOP) readings taken using dynamic contour tonometry (DCT) with IOP readings taken with Goldmann applanation tonometry (GAT) in eyes with glaucoma or ocular hypertension.
The present study included 100 eyes in 100 patients with glaucoma or ocular hypertension. After pachymetry DCT and GAT were performed. Intraocular pressures as measured with DCT and GAT were compared with one another and with central corneal thickness (CCT).
Mean DCT IOP measurements (20.1 +/- 4.3 mmHg) were significantly (p < 0.001) higher than GAT IOP values (17.9 +/- 4.7 mmHg). The mean difference between DCT and GAT measurements was 2.1 mmHg (range -3.4 to 9.7 mmHg). The difference followed a normal distribution. Measurements made with DCT and GAT correlated significantly with one another (Spearman's rho = 0.761, p < 0.001). Neither GAT nor DCT measurements showed a significant correlation with CCT (537 +/- 39 microm, range 458-656 microm). Multivariate regression analysis has shown that the difference between DCT and GAT is influenced significantly by ocular pulse amplitude (r = -0.334, p = 0.001) and it is not influenced by CCT (r = -0.106, p = 0.292).
In eyes with glaucoma or ocular hypertension, DCT facilitates suitable and reliable IOP measurements which are in good concordance with GAT readings. Variation in CCT cannot by itself explain the differences in measurements taken with DCT and GAT in a number of eyes.
比较动态轮廓眼压计(DCT)与Goldmann压平眼压计(GAT)在青光眼或高眼压症患者眼中所测的眼压读数。
本研究纳入了100例患有青光眼或高眼压症患者的100只眼。在测量角膜厚度后,进行DCT和GAT检查。比较DCT和GAT所测的眼压,并与中央角膜厚度(CCT)进行比较。
DCT测量的平均眼压值(20.1±4.3 mmHg)显著高于GAT测量的眼压值(17.9±4.7 mmHg)(p<0.001)。DCT和GAT测量值之间的平均差值为2.1 mmHg(范围为-3.4至9.7 mmHg)。该差值呈正态分布。DCT和GAT测量值之间存在显著相关性(Spearman相关系数ρ=0.761,p<0.001)。GAT和DCT测量值与CCT(537±39μm,范围458 - 656μm)均无显著相关性。多因素回归分析显示,DCT和GAT之间的差异受眼动脉搏动幅度显著影响(r = -0.334,p = 0.001),而不受CCT影响(r = -0.106,p = 0.292)。
在青光眼或高眼压症患者眼中,DCT有助于进行合适且可靠的眼压测量,与GAT读数具有良好的一致性。CCT的变化本身并不能解释在一些眼中DCT和GAT测量结果的差异。