[氟桂利嗪和双氢麦角胺治疗儿童偏头痛]

[Flunarizine and dihydroergotamine in the treatment of migraine in children].

作者信息

Lastra Martínez L, Herranz Fernández J, Arteaga Manjón-Cabez R

机构信息

Sección de Neuropediatría Hospital Nacional Marqués de Valdecilla, Facultad de Medicina, Universidad de Cantabria, Santander.

出版信息

An Esp Pediatr. 1990 Mar;32(3):213-8.

PMID:2189328

Abstract

We administer during 6 months in randomised way dihydroergotamine or flunarizine to 50 children affects of classical or common migraine. A significative improvement was estimated in frequency, intensity and duration of their crisis in 87% with dihydroergotamine and 79% with flunarizine, without significative differences from one to other. Dihydroergotamine was specially effective in children with vegetative lability. The secondary effects, 12% with dihydroergotamine and 20% with flunarizine, were trivial and advantageous even, without the necessity of stop the treatment in not any case.

摘要

我们以随机方式在6个月内对50名患有典型或普通偏头痛的儿童使用双氢麦角胺或氟桂利嗪。使用双氢麦角胺的患儿中87%在发作频率、强度和持续时间方面有显著改善，使用氟桂利嗪的为79%，两者之间无显著差异。双氢麦角胺对植物神经不稳定的儿童特别有效。双氢麦角胺的副作用发生率为12%，氟桂利嗪为20%，这些副作用微不足道甚至有益，在任何情况下都无需停止治疗。