Mre11-Rad50 复合物晶体提示分子体操。
Mre11-Rad50 complex crystals suggest molecular calisthenics.
机构信息
Department of Radiation Oncology, Department of Genetics and Cancer, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
出版信息
DNA Repair (Amst). 2011 Oct 10;10(10):1066-70. doi: 10.1016/j.dnarep.2011.07.008. Epub 2011 Sep 4.
Abstract
Recently published crystal structures of different Mre11 and Rad50 complexes show the arrangement of these proteins and imply dramatic ligand-induced rearrangements with important functional consequences.
摘要
最近发表的不同 Mre11 和 Rad50 复合物的晶体结构显示了这些蛋白质的排列方式，并暗示了剧烈的配体诱导重排，具有重要的功能后果。
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