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甲状腺疾病的流行病学。

The epidemiology of thyroid disease.

机构信息

Department of Endocrinology, Royal Free Hampstead NHS Trust, Pond Street, London NW3 2QG, UK.

出版信息

Br Med Bull. 2011;99:39-51. doi: 10.1093/bmb/ldr030.

DOI:10.1093/bmb/ldr030
PMID:21893493
Abstract

INTRODUCTION

Thyroid disorders are prevalent and their manifestations are determined by the dietary iodine availability.

SOURCES OF DATA

Data from screening large population samples from USA and Europe.

AREAS OF AGREEMENT

The most common cause of thyroid disorders worldwide is iodine deficiency, leading to goitre formation and hypothyroidism. In iodine-replete areas, most persons with thyroid disorders have autoimmune disease.

AREAS OF CONTROVERSY

Definition of thyroid disorders, selection criteria used, influence of age and sex, environmental factors and the different techniques used for assessment of thyroid function.

GROWING POINTS

Increasing incidence of well-differentiated thyroid cancer. Environmental iodine influences the epidemiology of non-malignant thyroid disease.

AREAS TIMELY FOR DEVELOPING RESEARCH

Iodine supplementation of populations with mild-to-moderate iodine deficiency. An evidence-based strategy for the risk stratification, treatment and follow-up of benign nodular thyroid disease. Is there any benefit in screening adults for thyroid dysfunction?

摘要

简介

甲状腺疾病较为常见,其临床表现取决于膳食碘的可获得性。

资料来源

来自美国和欧洲的大规模人群样本筛查数据。

共识领域

全世界最常见的甲状腺疾病病因是碘缺乏,导致甲状腺肿和甲状腺功能减退。在碘充足地区,大多数甲状腺疾病患者患有自身免疫性疾病。

争议领域

甲状腺疾病的定义、使用的选择标准、年龄和性别、环境因素以及评估甲状腺功能的不同技术的影响。

新的研究领域

分化良好的甲状腺癌的发病率不断上升。环境碘会影响非恶性甲状腺疾病的流行病学。

需要及时开展研究的领域

对轻度至中度碘缺乏人群进行碘补充。良性结节性甲状腺疾病的风险分层、治疗和随访的循证策略。筛查成年人甲状腺功能障碍是否有益?

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