Evelina Childrens Hospital, London, UK.
Nephron Clin Pract. 2011;119 Suppl 2:c97-106. doi: 10.1159/000331755. Epub 2011 Aug 26.
To describe the demographics of the paediatric RRT population under the age of 16 years in the UK and to analyse changes in demography with time.
Extraction and analysis of data from the UK Renal Registry (UKRR).
There were 751 children <16 years old with established renal failure (ERF) in the UK in December 2009. The reported prevalence under the age of 16 years was 65 per million age related population (pmarp) and the reported incidence 9.3 pmarp. The incidence and prevalence for South Asian patients was much higher than that of the White and Black populations. Of the patients for whom a primary renal diagnosis had been reported, renal dysplasia ± reflux was the most common cause of ERF accounting for 34.0% of prevalent cases. There has been growth in treatment numbers in all paediatric renal centres between 1995 and 2010. Whilst the rate of transplantation within 90 days of commencing RRT has remained at around 25-30% of patients, the use of HD has increased by 4% at the expense of PD.
The paediatric ERF population continued to expand with a slow increase in both incidence and prevalence rates. The high incidence in patients from ethnic minority groups will lead to a greater proportion of the population being from these groups in time. To maintain the high proportion of engrafted patients it will be necessary to encourage living donation in the ethnic minority population.
描述英国年龄在 16 岁以下的儿科肾脏替代治疗（RRT）人群的人口统计学特征，并分析随时间推移人口统计学特征的变化。
从英国肾脏注册处（UKRR）提取和分析数据。
2009 年 12 月，英国有 751 名年龄<16 岁的儿童患有终末期肾衰竭（ERF）。报告的年龄<16 岁人群患病率为 65/百万年龄相关人群（pmarp），发病率为 9.3 pmarp。南亚患者的发病率和患病率远高于白人和黑人。在报告了原发性肾脏诊断的患者中，肾发育不良±反流是 ERF 的最常见原因，占现有病例的 34.0%。1995 年至 2010 年间，所有儿科肾脏中心的治疗人数都有所增加。虽然开始 RRT 后 90 天内移植的比例保持在患者的 25-30%左右，但 HD 的使用增加了 4%，而 PD 的使用减少了 4%。
儿科 ERF 人群仍在继续扩大，发病率和患病率都缓慢上升。少数民族群体患者的高发病率将导致该群体在未来的人口中占更大比例。为了保持高比例的移植患者，有必要鼓励少数民族群体进行活体捐赠。
