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天奈普汀对 3 个月观察期间抑郁障碍患者认知功能的影响。

Effect of tianeptine on cognitive functions in patients with depressive disorders during a 3-month observation.

机构信息

Institute of Psychology, University of Opole, Poland.

出版信息

Psychiatr Danub. 2011 Sep;23 Suppl 1:S18-22.

PMID:21894095
Abstract

OBJECTIVE

The authors put forward the hypotheses that during a three-month treatment with tianeptine in patients with depressive disorders there is an improvement in the short-term memory, reaction time and attention.

SUBJECT AND METHODS

20 patients suffering from depression, were included in the study. During the entire research period all patients were treated with monotherapy with tianeptine. Cognitive function measurements were performed using the Vienna Test System.

RESULTS

Our study showed an improvement in the all the assessed functions: patients treated with tianeptine had better performance in tests measuring short term memory and learning processes as well as reaction time and attention.

CONCLUSION

In conclusion, the study shows that tianeptine improves cognitive functions in depressed patients.

摘要

目的

作者提出假设,即接受 3 个月的噻奈普汀治疗后,抑郁障碍患者的短期记忆、反应时间和注意力会得到改善。

对象和方法

研究纳入 20 名患有抑郁症的患者。在整个研究期间,所有患者均接受噻奈普汀单药治疗。采用维也纳测试系统进行认知功能测量。

结果

我们的研究显示所有评估的功能均有改善:接受噻奈普汀治疗的患者在测试短期记忆和学习过程以及反应时间和注意力的测试中表现更好。

结论

综上所述,该研究表明噻奈普汀可改善抑郁患者的认知功能。

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1
Effect of tianeptine on cognitive functions in patients with depressive disorders during a 3-month observation.天奈普汀对 3 个月观察期间抑郁障碍患者认知功能的影响。
Psychiatr Danub. 2011 Sep;23 Suppl 1:S18-22.
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Antidepressant and anxiolytic activities of tianeptine: an overview of clinical trials.噻奈普汀的抗抑郁和抗焦虑活性:临床试验综述
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Long-term use of tianeptine in 380 depressed patients.
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[Patients treated for one year with tianeptine. Results at one of the centers of South-Eastern France].[接受噻奈普汀治疗一年的患者。法国东南部某中心的结果]
Encephale. 1990 May-Jun;16(3):181-7.
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Cognitive remission: a novel objective for the treatment of major depression?
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Influence of Pharmacotherapy on Cognitive Functions in Depression: A Review of the Literature.药物治疗对抑郁症认知功能的影响:文献综述
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