Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Chem Soc Rev. 2012 Jan 21;41(2):643-65. doi: 10.1039/c1cs15140a. Epub 2011 Sep 6.
In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituent and the nature of the electrophile and the nucleophile. This overview should allow chemists to gain insight into the factors governing the regioselectivity in aziridinium ring openings (81 references).
在这篇评论中，将讨论通过中间氮丙啶盐开环非活化的 2-取代氮丙啶。重点将放在观察到的区域选择性与固有结构特征（如 C2 氮丙啶取代基的性质、亲电和亲核试剂的性质）之间的关系上。这篇综述应该可以让化学家深入了解影响氮丙啶环开环区域选择性的因素（81 篇参考文献）。
