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单核细胞增生李斯特菌心包炎的成功治疗:病例报告及文献综述

Successful management of Listeria monocytogenes pericarditis: case report and review of the literature.

作者信息

Dias Vasco, Cabral Sofia, Anjo Diana, Vieira Miguel, Antunes Nuno, Carvalheiras Graziela, Gomes Catarina, Meireles Ana, Mendonça Teresa, Torres Severo

机构信息

Department of Cardiology, Santo António General Hospital - Oporto Hospital Centre, Porto, Portugal.

出版信息

Acta Cardiol. 2011 Aug;66(4):537-8. doi: 10.1080/ac.66.4.2126608.

Abstract

Listeria monocytogenes, although an uncommon cause of illness in the general population, is feared principally because of the morbidity and mortality associated with CNS infections. Cardiovascular involvement with L. monocytogenes is very rare, and has been limited to endocarditis. We describe a case of Listeria pericarditis, which occurred in a 60-year-old man with Child-Pugh B cirrhosis who presented to the emergency department with asthenia, anorexia, and respiratory distress. The echocardiogram showed severe pericardial effusion and after pericardiocentesis, L. monocytogenes was isolated in the culture of pericardial fluid. After surgical pericardiectomy with draining of the pericardial effusion and antibiotic treatment with ampicillin, the patient experienced a slow, but full recovery. Documentation of L. monocytogenes pericarditis is an extremely rare entity with very scarce reports in medical literature, and is usually associated with a very poor prognosis. A case report is presented together with a review of the literature.

摘要

单核细胞增生李斯特菌虽然在普通人群中并非常见的致病原因,但主要因其与中枢神经系统感染相关的发病率和死亡率而令人担忧。单核细胞增生李斯特菌累及心血管系统的情况非常罕见,且仅限于心内膜炎。我们报告一例李斯特菌性心包炎病例,该病例发生在一名60岁患有Child-Pugh B级肝硬化的男性身上,他因乏力、厌食和呼吸窘迫就诊于急诊科。超声心动图显示严重心包积液,心包穿刺术后,心包液培养分离出单核细胞增生李斯特菌。在进行心包积液引流的外科心包切除术并使用氨苄西林进行抗生素治疗后,患者缓慢但完全康复。单核细胞增生李斯特菌性心包炎的记录是一种极其罕见的疾病,医学文献中报道极少,且通常预后很差。本文呈现了一例病例报告并对文献进行了综述。

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