Department of Organic Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia.
Nat Prod Res. 2012;26(8):696-702. doi: 10.1080/14786419.2010.550580. Epub 2011 Sep 6.
The chemical composition of Rhodobryum ontariense (Kindb.) Kindb. has not been previously investigated. Fatty acids of this moss were analysed qualitatively and quantitatively with an aim to identify its corresponding pattern. A total of eight fatty acids were identified including two acetylenic ones: 9,12,15-octadecatrien-6-ynoic acid (42.26%), α-linolenic acid (20.32%), palmitic acid (14.31%), 9,12-octadecadienoic-6-ynoic acid (13.31%), linoleic acid (5.25%), oleic acid (2.47%), stearic acid (1.14%) and γ-linolenic acid (0.92%). To our knowledge, this is the first record of acetylenic fatty acids in the genus Rhodobryum. In general, acetylenic fatty acids vary considerably among different moss groups and have been used as a chemotaxonomic character in bryophyte classifications. Other species of Rhodobryum from Asia have been traditionally used in ethno medicine by indigenous cultures. Two fatty acids of those reported here, 9,12,15-octadecatrien-6-ynoic and α-linolenic acid, have known cardio protective activity, which supports respective claims of traditional herbal use of these mosses.
先前并未研究过北美金发藓（Rhodobryum ontariense (Kindb.) Kindb.）的化学成分。本研究旨在确定其相应模式，对这种苔藓的脂肪酸进行了定性和定量分析。共鉴定出 8 种脂肪酸，其中包括两种炔酸：9,12,15-十八碳三烯-6-炔酸（42.26%）、α-亚麻酸（20.32%）、棕榈酸（14.31%）、9,12-十八碳二烯-6-炔酸（13.31%）、亚油酸（5.25%）、油酸（2.47%）、硬脂酸（1.14%）和γ-亚麻酸（0.92%）。据我们所知，这是金发藓属中首次记录到炔酸脂肪酸。总的来说，炔酸脂肪酸在不同的苔藓群中差异很大，并且已被用作苔藓植物分类中的化学分类学特征。亚洲的其他金发藓物种在传统上被土著文化用于民族医学。这里报告的两种脂肪酸，9,12,15-十八碳三烯-6-炔酸和α-亚麻酸，具有已知的心脏保护活性，这支持了这些苔藓植物传统草药用途的说法。
