Department of Endodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USA.
Dent Traumatol. 2012 Feb;28(1):25-32. doi: 10.1111/j.1600-9657.2011.01049.x. Epub 2011 Sep 5.
Mineral trioxide aggregate (MTA) has over the last two decades begun to take the place of calcium hydroxide (CH) in the treatment of a variety of pulpal and periodontal healing complications following dental trauma. These conditions include teeth with: (i) exposed pulps, (ii) immature roots and pulp necrosis, (iii) root fractures and pulp necrosis located in the coronal part of the pulps, and (iv) external infection-related (inflammatory) root resorption. The main reasons for replacing CH with MTA in these situations have generally been the delayed effect when using CH to induce hard tissues, the quality of such induced hard tissues, and finally the dentin weakening effect of CH, which in some instances lead to cervical root fractures in immature teeth. MTA appears, from a relatively few clinical studies, to overcome these shortcomings of CH. The lack of long-term clinical studies, however, may warrant a certain reservation in an unrestricted replacement of CH with MTA. A definite need for randomized clinical studies comparing CH and MTA in trauma healing situations is urgently needed.
矿物三氧化物聚合体（MTA）在过去二十年中开始取代氢氧化钙（CH），用于治疗各种牙髓和牙周愈合并发症，这些并发症包括：（i）暴露的牙髓，（ii）未成熟的牙根和牙髓坏死，（iii）牙根折裂和位于牙髓冠部的牙髓坏死，以及（iv）与外部感染相关的（炎症性）牙根吸收。在这些情况下，用 MTA 替代 CH 的主要原因通常是 CH 诱导硬组织的延迟作用，以及这种诱导硬组织的质量，最后是 CH 的牙本质弱化作用，在某些情况下会导致未成熟牙齿的颈根骨折。从相对较少的临床研究来看，MTA 似乎克服了 CH 的这些缺点。然而，缺乏长期的临床研究可能需要对 CH 进行一定程度的保留，而不是无限制地用 MTA 替代 CH。迫切需要进行比较 CH 和 MTA 在创伤愈合情况下的随机临床研究。
