Center for Nanomaterials and Sensor Development, SUNY Stony Brook, Stony Brook, NY 11794-2275,USA.
J Breath Res. 2011 Sep;5(3):037110. doi: 10.1088/1752-7155/5/3/037110. Epub 2011 Sep 6.
This paper describes a novel concept of a three-nanosensor array microsystem that may potentially serve as a coarse diagnostic tool handheld breath analyzer to provide a first detection device. The specification and performance of a simple metal oxide nanosensor operating between three distinct temperatures are discussed, focusing on the need for a noninvasive blood cholesterol monitor. Interfacing the sensor array to an integrated circuit for electrical readout and temperature control provides a complete microsystem capable of capturing a single exhaled breath and analyzing it with respect to the relative content of isoprene, carbon dioxide and ammonia gas. This inexpensive sensor technology may be used as a personalized medical diagnostics tool in the near future.
本文描述了一种新型的三纳米传感器阵列微系统概念,该系统可能作为一种手持式呼吸分析仪的粗诊断工具,提供初步的检测设备。本文讨论了一种在三个不同温度下工作的简单金属氧化物纳米传感器的规格和性能,重点是需要一种非侵入性的血液胆固醇监测仪。将传感器阵列与集成电路接口进行电读出和温度控制,提供了一个完整的微系统,能够捕获单次呼气,并分析其异戊二烯、二氧化碳和氨气的相对含量。这种廉价的传感器技术可能在不久的将来被用作个性化医疗诊断工具。