Ohmi Aki, Tsukamoto Atsushi, Ohno Koichi, Uchida Kazuyuki, Nishimura Ryohei, Fukushima Kenjiro, Takahashi Masashi, Nakashima Ko, Fujino Yasuhito, Tsujimoto Hajime
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
J Vet Med Sci. 2012 Jan;74(1):59-64. doi: 10.1292/jvms.11-0352. Epub 2011 Sep 6.
Medical records of dogs with colorectal polyps were retrospectively reviewed, and clinical presentation of inflammatory colorectal polyps in miniature dachshunds was evaluated. Of 33 dogs found to have colorectal polyps, miniature dachshunds were markedly over-represented with 16 dogs (48%), of which 12 (75%) were found to have inflammatory polyps. Multiple polyps localized between the rectum and the descending colon was the most common finding in miniature dachshunds with inflammatory polyps. Twenty dogs (80%) out of 25 miniature dachshunds with inflammatory colorectal polyps responded to immunosuppressive therapy using prednisolone and cyclosporine. The results of this study indicate that miniature dachshunds are predisposed to develop inflammatory colorectal multiple polyps, for which immunosuppressive therapy may be a treatment option.
对患有大肠息肉的犬类病历进行回顾性研究,并评估迷你腊肠犬炎症性大肠息肉的临床表现。在33只被发现患有大肠息肉的犬中,迷你腊肠犬明显占比过高,有16只(48%),其中12只(75%)被发现患有炎症性息肉。直肠和降结肠之间存在多个息肉是患有炎症性息肉的迷你腊肠犬最常见的表现。25只患有炎症性大肠息肉的迷你腊肠犬中有20只(80%)对使用泼尼松龙和环孢素的免疫抑制疗法有反应。本研究结果表明,迷你腊肠犬易患炎症性大肠多发性息肉,免疫抑制疗法可能是一种治疗选择。