肺腺癌转移至虹膜，类似于 Cogan-Reese 综合征。
Metastatic lung adenocarcinoma to the iris mimicking Cogan-Reese syndrome.
机构信息
Department of Ophthalmology, Dean McGee Eye Institute, University of Oklahoma College of Medicine, Oklahoma City, OK 73104, USA.
出版信息
J Glaucoma. 2012 Oct-Nov;21(8):567-9. doi: 10.1097/IJG.0b013e3182208a2e.
PURPOSE
Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome.
METHODS
A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy.
RESULTS
Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma.
CONCLUSIONS
Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.
目的
报告一例转移性肺癌至虹膜，类似于 Cogan-Reese 综合征。
方法
一名 61 岁女性，患有非小细胞肺癌，表现为单侧眼内压升高（IOP）和多个色素沉着虹膜结节，伴有前虹膜膜。患者的 IOP 不能通过药物控制，因此她接受了小梁切除术和同时的虹膜活检。
结果
组织病理学显示虹膜表面的腺体上皮增生，符合转移性肺腺癌。
结论
虹膜转移有多种表现，任何有癌症病史的患者出现虹膜病变都必须考虑转移疾病。转移性腺癌在虹膜上形成虹膜膜和结节可能类似于 Cogan-Reese 综合征。
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