Holló Gábor, Naghizadeh Farzaneh
Department of Ophthalmology, Semmelweis University, Budapest - Hungary.
Eur J Ophthalmol. 2014 Sep-Oct;24(5):797-9. doi: 10.5301/ejo.5000465. Epub 2014 Apr 4.
To describe the characteristic optical coherence tomography (OCT) findings of the iris in Cogan-Reese syndrome.
A 63-year-old woman was referred for consultation due to diffuse pigmentation of the iris and elevated intraocular pressure (IOP) in the left eye. The clinical examination revealed Cogan-Reese syndrome with pedunculated iris outcroppings on the entire iris surface, and no peripheral anterior synechia. The right eye was normal with normal IOP.
Imaging the left iris with the CAM-L cornea lens adapter of the Optovue Fourier-domain OCT (RTVue-OCT) showed a folded iris surface, an increased total iris thickness, and an increased distance between the anterior and posterior iris layers, compared to those of the healthy right eye.
Traction by the pathological endothelial cell layer that covers the iris surface in Cogan-Reese syndrome causes characteristic OCT signs in the iris. Detection of the folded iris surface, increase of iris thickness, and increase of the distance between the anterior and posterior iris layers with RTVue-OCT anterior segment examination may promote the correct diagnosis and may help the clinician to discriminate Cogan-Reese syndrome from true iris nevi or iris melanoma.
描述科根 - 里斯综合征（Cogan-Reese syndrome）患者虹膜的特征性光学相干断层扫描（OCT）表现。
一名63岁女性因左眼虹膜弥漫性色素沉着和眼压升高前来咨询。临床检查发现患有科根 - 里斯综合征，整个虹膜表面有带蒂的虹膜赘生物，且无前房角粘连。右眼正常，眼压正常。
使用Optovue傅里叶域OCT（RTVue-OCT）的CAM-L角膜透镜适配器对左眼虹膜进行成像，结果显示与健康右眼相比，虹膜表面呈折叠状，虹膜总厚度增加，虹膜前后层之间的距离增大。
科根 - 里斯综合征中覆盖虹膜表面的病理性内皮细胞层产生的牵引力导致虹膜出现特征性OCT表现。通过RTVue-OCT眼前节检查检测到虹膜表面折叠、虹膜厚度增加以及虹膜前后层之间距离增加，可能有助于正确诊断，并帮助临床医生将科根 - 里斯综合征与真性虹膜痣或虹膜黑色素瘤区分开来。
