Ukah Cornelius O, Oluwasola Olayiwola A
Department of Pathology, University College Hospital, Ibadan, Oyo State, Nigeria.
J Cytol. 2011 Jul;28(3):111-3. doi: 10.4103/0970-9371.83467.
Although open surgical biopsy is the 'gold standard' for diagnosis of palpable breast lesions, in recent years two types of minimally invasive breast biopsy techniques, core needle biopsy and fine needle aspiration biopsy (FNAB), have become established for the diagnostic evaluation of palpable breast lesions.
This study was undertaken to evaluate the clinical effectiveness of FNAB as a first line diagnostic procedure in the management of patients with breast lumps in University College Hospital (UCH), Ibadan, using the suggested thresholds for cytology performance as recommended by the United Kingdom National Health Services Breast Screening Programme (NHSBSP).
A 10-year retrospective cohort study carried out in the Pathology Department of UCH.
All FNAB and histologically diagnosed cases of breast lesions in the pathology department between January 1996 and December 2005 were reviewed. The cytological diagnoses were then categorized into one of five diagnostic categories in accordance with the recommendations of the NHSBSP.
The positive predictive value for malignancy was 99.3% with a complete sensitivity of 97.7% and specificity (full) of 94.2%.
The high quality assurance measures obtained in this study affirms FNAB as a clinically effective diagnostic procedure for breast lesions.
尽管开放式手术活检是可触及乳腺病变诊断的“金标准”，但近年来，两种微创乳腺活检技术，即粗针活检和细针穿刺抽吸活检（FNAB），已被确立用于可触及乳腺病变的诊断评估。
本研究旨在采用英国国家医疗服务体系乳腺筛查计划（NHSBSP）推荐的细胞学检查性能建议阈值，评估在伊巴丹大学学院医院（UCH）对乳腺肿块患者进行管理时，FNAB作为一线诊断程序的临床有效性。
在UCH病理科进行的一项为期10年的回顾性队列研究。
回顾了1996年1月至2005年12月期间病理科所有经FNAB和组织学诊断的乳腺病变病例。然后根据NHSBSP的建议，将细胞学诊断分为五个诊断类别之一。
恶性肿瘤的阳性预测值为99.3%，完全敏感性为97.7%，特异性（完全）为94.2%。
本研究中获得的高质量保证措施证实FNAB是一种用于乳腺病变的临床有效诊断程序。
