Sharma Abhishek, Bhutoria Bhawna, Guha Debasish, Bhattacharya Subodh, Wasim Nazir Abdul
Department of Pathology, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
J Cytol. 2011 Jul;28(3):121-3. doi: 10.4103/0970-9371.83470.
Rhabdomyosarcoma (RMS) is an aggressive malignant soft tissue tumor that arises from primitive striated muscle cells called rhabdomyoblasts. RMS is a rare tumor in adults, and involvement of the sinonasal area is extremely rare, comprising only 1.5% of all reported head and neck RMSs. Alveolar RMS, mainly seen in adults, has the worst prognosis. Incidence of lymph node metastases is more common in this type compared with the other forms. Fine needle aspiration cytology (FNAC) has been used extensively in the diagnosis of metastatic malignancies. However, metastatic soft tissue sarcomas are often overlooked, primarily due to the low frequency with which they occur. Here, we report a rare case of metastatic alveolar RMS in the cervical lymph nodes of an 18-year-old girl that was detected by FNAC. After 6 months, the patient came with a huge mass involving the nasal vestibule and the upper lip. Histology of both the main mass and the lymph nodes revealed alveolar RMS.
横纹肌肉瘤（RMS）是一种侵袭性恶性软组织肿瘤，起源于称为横纹肌母细胞的原始横纹肌细胞。RMS在成人中是一种罕见肿瘤，鼻窦区域受累极为罕见，仅占所有报道的头颈部RMS的1.5%。主要见于成人的腺泡状RMS预后最差。与其他类型相比，这种类型的淋巴结转移发生率更常见。细针穿刺细胞学检查（FNAC）已广泛用于转移性恶性肿瘤的诊断。然而，转移性软组织肉瘤常常被忽视，主要是因为它们的发生率较低。在此，我们报告一例18岁女孩经FNAC检测出的颈部淋巴结转移性腺泡状RMS罕见病例。6个月后，患者出现累及鼻前庭和上唇的巨大肿块。主要肿块和淋巴结的组织学检查均显示为腺泡状RMS。
