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老年患者鼻腔胚胎性横纹肌肉瘤:病例报告及文献复习

Embryonal rhabdomyosarcoma of the nose in an elderly patient, case report and review of the literature.

作者信息

Jund R, Leunig A, Hagedorn H, Nerlich A, Grevers G

机构信息

Department of ENT, Head and Neck Surgery, Ludwig-Maximilians-Universität München, Klinikum Grosshadern, Germany.

出版信息

Auris Nasus Larynx. 1998 Dec;25(4):445-50. doi: 10.1016/s0385-8146(98)00043-1.

Abstract

Embryonal rhabdomyosarcoma of the head and neck is very rare in adults. We report on an embryonal rhabdomyosarcoma of the nose, occuring in a 74-year-old female patient presenting with nasal congestion as the only clinical symptom. Suspected to be an amelanotic melanoma, further biopsies and histological examinations provided the correct diagnosis. She first underwent a course of chemotherapy which led to a partial shrinkage of the tumor mass which was followed by a complete resection of the residual tumor mass. Biologic behaviour of this tumor must be fully appreciated as treatment is interdisciplinary. Rhabdomyosarcoma should be considered in the differential diagnosis of tumors of the nose and paranasal sinuses not only in children, but also in adults.

摘要

头颈部胚胎性横纹肌肉瘤在成人中极为罕见。我们报告一例发生于鼻部的胚胎性横纹肌肉瘤,患者为74岁女性,唯一的临床症状是鼻塞。最初怀疑是无色素性黑色素瘤,进一步的活检和组织学检查给出了正确诊断。她首先接受了一个疗程的化疗,肿瘤体积部分缩小,随后对残留肿瘤进行了完整切除。由于该肿瘤的治疗需要多学科协作,因此必须充分了解其生物学行为。在鼻腔和鼻窦肿瘤的鉴别诊断中,不仅儿童,成人也应考虑横纹肌肉瘤。

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