Divya Kn, Jayashree K
Department of Pathology, Medical College (VIMS), Bellary, Karnataka, India.
J Cytol. 2011 Jul;28(3):127-30. doi: 10.4103/0970-9371.83472.
Neoplastic urothelium has the capacity to demonstrate enormous plasticity. A variety of unusual morphological variants of urothelial carcinoma have been described. Micropapillary variant of urothelial carcinoma is a rare and recently described bladder tumor, associated with poor prognosis. We present the cytological features of micropapillary urothelial carcinoma in a 65-year-old man with bladder mass. The cytological features include tightly cohesive clusters of micropapillary component admixed with urothelial carcinoma. Histopathological sections showed small nests of tumor cells residing within the lacunae. Establishing a diagnosis of micropapillary urothelial carcinoma indicates a high-grade and high-stage tumor with poor outcome, requiring an aggressive therapy. It is thus important for the cytopathologist to recognise micropapillary variant of urothelial carcinoma, for early and better management of patients with bladder tumor.
肿瘤性尿路上皮具有表现出巨大可塑性的能力。已经描述了尿路上皮癌的多种不寻常形态学变体。尿路上皮癌的微乳头变体是一种罕见的且最近才被描述的膀胱肿瘤，与预后不良相关。我们展示了一名患有膀胱肿块的65岁男性微乳头尿路上皮癌的细胞学特征。细胞学特征包括微乳头成分紧密聚集的细胞团与尿路上皮癌混合存在。组织病理学切片显示肿瘤细胞小巢位于腔隙内。诊断微乳头尿路上皮癌表明是一种高级别、高分期且预后不良的肿瘤，需要积极治疗。因此，对于细胞病理学家来说，识别尿路上皮癌的微乳头变体对于膀胱肿瘤患者的早期和更好管理很重要。
