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阿育吠陀疗法对类风湿性关节炎的疗效:一项纵向研究的横断面经验概况

The efficacy of Ayurvedic treatment for rheumatoid arthritis: Cross-sectional experiential profile of a longitudinal study.

作者信息

Krishna Kumar P R

机构信息

BAMS, Ayurvedic Trust, Trichy Road, Ramanathapuram, Coimbatore, Tamil Nadu, India.

出版信息

Int J Ayurveda Res. 2011 Jan;2(1):8-13. doi: 10.4103/0974-7788.83177.

Abstract

CONTEXT

Allopathic and Ayurvedic physicians collaborated on a study of traditional medicine, which was sponsored by the World Health Organization.

AIMS

The aim of the study was to test the efficacy and safety of Ayurvedic treatment for rheumatoid arthritis (RA).

SETTINGS AND DESIGN

This study was conducted at the Ayurvedic Trust, Coimbatore, India.

MATERIALS AND METHODS

In this unique study of classical Ayurvedic treatment for RA, allopathic physicians enrolled a total of 290 patients with a confirmed diagnosis of RA over a 7-year period, and once every 6 weeks evaluated Ayurvedic treatment outcomes on the basis of American Rheumatism Association criteria: grip strength, walking time, number of swollen and painful joints, joint count, functional class, erythrocyte sedimentation rate, and rheumatoid factor. Ayurvedic physicians administered individualized treatment, closely adhering to principles set forth in classical Ayurvedic texts. The duration of treatment varied from 1 to 6 months.

STATISTICAL ANALYSIS USED

Due to limitations in computer technology in the 1970s, the data were not computerized. Therefore, data for 12 months at a time were analyzed, using repeated measures t-test. Measures of central tendency (means) and probability values were reported. Results from the patients enrolled and discharged at the end of the first year of the study (N = 33) are presented in this paper.

RESULTS

There was statistically significant improvement in all parameters from admission to discharge.

CONCLUSIONS

The results indicated that classical Ayurvedic treatment was effective in this first cohort of patients who completed treatment. Even patients with severe functional limitations showed significant improvement. Although there was no control group, the results are positive enough to warrant further study of classical Ayurvedic treatment for RA in controlled trials.

摘要

背景

对抗疗法医生和阿育吠陀医生合作开展了一项由世界卫生组织赞助的传统医学研究。

目的

该研究的目的是测试阿育吠陀疗法治疗类风湿性关节炎(RA)的疗效和安全性。

设置与设计

本研究在印度哥印拜陀的阿育吠陀信托机构进行。

材料与方法

在这项针对RA的经典阿育吠陀疗法的独特研究中,对抗疗法医生在7年时间里共招募了290名确诊为RA的患者,并每6周依据美国风湿病协会标准评估一次阿育吠陀治疗效果:握力、步行时间、肿胀和疼痛关节数量、关节计数、功能分级、红细胞沉降率和类风湿因子。阿育吠陀医生进行个体化治疗,严格遵循经典阿育吠陀文献中阐述的原则。治疗时长从1个月到6个月不等。

所用统计分析方法

由于20世纪70年代计算机技术的限制,数据未进行计算机处理。因此,每次对12个月的数据进行分析,采用重复测量t检验。报告了集中趋势测量值(均值)和概率值。本文呈现了研究第一年结束时入组并出院的患者(N = 33)的结果。

结果

从入院到出院,所有参数均有统计学意义上的显著改善。

结论

结果表明,经典阿育吠陀疗法对完成治疗的首批患者有效。即使是功能严重受限的患者也有显著改善。尽管没有对照组,但这些结果足以支持在对照试验中进一步研究经典阿育吠陀疗法治疗RA。

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