Aabideen Kanakkande, Moulton Lawrence Stephen, Sills John
Department of Paediatrics, Whiston Hospital, Merseyside, UK.
J Pharmacol Pharmacother. 2011 Jul;2(3):189-90. doi: 10.4103/0976-500X.83286.
Paracetamol is one of the most commonly used drugs both over the counter and on prescription. Liquid paracetamol is available over the counter all over the world. Most commonly available concentrations are 120 mg/5 ml and 250 mg/5 ml. Many parents and healthcare professionals assume that doses available in different countries are similar. However, 500 mg/5 ml bottle is available in some countries including the United Kingdom. This leaves a potential for accidental overdose with therapeutic intent. We have reviewed the experience of diagnosing and managing an interesting case of paracetamol over dosage caused by several ingestions over 24 hours period (staggered paracetamol over dosage). It highlights the importance of communication between health professionals and parents while managing common medical problems.
对乙酰氨基酚是最常用的非处方药和处方药之一。全球各地的非处方药柜台均有液体对乙酰氨基酚出售。最常见的浓度为120毫克/5毫升和250毫克/5毫升。许多家长和医护人员认为不同国家的可用剂量相似。然而,包括英国在内的一些国家有500毫克/5毫升的瓶装产品。这就有可能在治疗目的下意外过量用药。我们回顾了一例有趣的对乙酰氨基酚过量病例的诊断和处理经验,该病例是在24小时内多次服药导致的(错开的对乙酰氨基酚过量)。它凸显了医护人员与家长在处理常见医疗问题时沟通的重要性。