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口服补液疗法用于术前液体和电解质管理。

Oral rehydration therapy for preoperative fluid and electrolyte management.

机构信息

School of Nutrition & Dietetics, Kanagawa University of Human Services, Yokosuka, Kanagawa 238-8522, Japan.

出版信息

Int J Med Sci. 2011;8(6):501-9. doi: 10.7150/ijms.8.501. Epub 2011 Aug 25.

Abstract

AIM

Preoperative fluid and electrolyte management is usually performed by intravenous therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for preoperative fluid and electrolyte management of surgical patients.

METHODS

The study consisted of two studies, designed as a prospective observational study. In a pilot study, 20 surgical patients consumed 1000 mL of an oral rehydration solution (ORS) until 2 h before induction of general anesthesia. Parameters such as serum electrolyte concentrations, fractional excretion of sodium (FENa) as an index of renal blood flow, volume of esophageal-pharyngeal fluid and gastric fluid (EPGF), and patient satisfaction with ORT were assessed. In a follow-up study to assess the safety of ORT, 1078 surgical patients, who consumed ORS until 2 h before induction of general anesthesia, were assessed.

RESULTS

In the pilot study, water, electrolytes, and carbohydrate were effectively and safely supplied by ORT. The FENa value was increased at 2 h following ORT. The volume of EPGF collected following the induction of anesthesia was 5.3±5.6 mL. In the follow-up study, a small amount of vomiting occurred in one patient, and no aspiration occurred in the patients.

CONCLUSION

These results suggest that ORT is a safe and effective therapy for the preoperative fluid and electrolyte management of selected surgical patients.

摘要

目的

术前液体和电解质管理通常通过静脉治疗进行。我们研究了口服补液疗法(ORT)用于手术患者术前液体和电解质管理的安全性和有效性。

方法

该研究由两项研究组成,设计为前瞻性观察研究。在一项试点研究中,20 名手术患者在全身麻醉诱导前 2 小时内饮用 1000 毫升口服补液溶液(ORS)。评估了血清电解质浓度、钠排泄分数(FENa)作为肾血流量的指标、食管-咽部液和胃液(EPGF)的体积以及患者对 ORT 的满意度等参数。在一项评估 ORT 安全性的后续研究中,评估了 1078 名在全身麻醉诱导前 2 小时内饮用 ORS 的手术患者。

结果

在试点研究中,ORT 有效地、安全地提供了水、电解质和碳水化合物。ORT 后 2 小时 FENa 值增加。麻醉诱导后收集的 EPGF 量为 5.3±5.6 毫升。在后续研究中,一名患者出现少量呕吐,患者无吸入。

结论

这些结果表明,ORT 是一种安全有效的治疗方法,可用于选择的手术患者的术前液体和电解质管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81d8/3167099/bf9d193b925d/ijmsv08p0501g01.jpg

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