胃碰撞瘤：一例腺癌合并胃肠道间质瘤
Collision tumor of the stomach: a case of an adenocarcinoma and a gastrointestinal stromal tumor.
作者信息
Idema D L M, Daryanani D, Sterk L M T, Klaase J M
机构信息
Department of Surgery, Medisch Spectrum Twente, The Netherlands.
出版信息
Case Rep Gastroenterol. 2008 Sep;2(3):456-60. doi: 10.1159/000129707. Epub 2008 Nov 15.
A collision tumor of the stomach is a rare event. We report the case of a collision tumor of the stomach consisting of an adenocarcinoma and a gastrointestinal stromal tumor (GIST). This is, to our knowledge, the second report in the literature of such a case. A 71-year-old man with abdominal discomfort underwent an esophagogastroduodenoscopy which revealed a tumor of the oesophagogastric junction. A total gastrectomy was performed. Histologic examination showed a mixed tumor consisting of a primary adenocarcinoma and multiple nodules of GIST. The adenocarcinoma showed both diffuse and intestinal growth, angio-invasion and metastasis to lymph nodes. The GIST tumor cells were strongly immunoreactive to CD117 and CD34. Based on mitotic index, size and cytonuclear details, the biological behavior of this GIST tumor was supposed to be benign. This case reports the rare finding of a collision tumor consisting of an adenocarcinoma and a GIST with an unknown etiology.
胃碰撞瘤是一种罕见的情况。我们报告一例胃碰撞瘤，其由腺癌和胃肠道间质瘤（GIST）组成。据我们所知，这是文献中关于此类病例的第二篇报道。一名71岁有腹部不适的男性接受了食管胃十二指肠镜检查，发现食管胃交界处有一个肿瘤。进行了全胃切除术。组织学检查显示为混合性肿瘤，由原发性腺癌和多个GIST结节组成。腺癌呈弥漫性和肠型生长，有血管侵犯并转移至淋巴结。GIST肿瘤细胞对CD117和CD34呈强免疫反应性。根据有丝分裂指数、大小和细胞核细节，该GIST肿瘤的生物学行为被认为是良性的。本病例报告了由腺癌和GIST组成的病因不明的罕见碰撞瘤。
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