Mansueto Pasquale, Carroccio Antonio, Corsale Sveva, Di Lorenzo Gabriele, Di Prima Lidia, Pirrone Giuseppe, Florena Ada Maria, Di Fede Gaetana
Dipartimento di Medicina Clinica e delle Patologie Emergenti, University of Palermo, Italy.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2008.0781. Epub 2009 Sep 7.
Clinical presentation of Crohn's disease (CD) may be variable according to the location and the intensity of the inflammation. Some patients may have atypical symptoms which could delay the diagnosis. We report the first case of chronic urticaria related to a subclinical, complicated CD. Although the pathologic mechanism of this association was unclear in our patient, this case suggests that in patients with unexplained chronic urticaria it is opportune to investigate for a possible CD, even if there are no or few specific symptoms of intestinal inflammatory disease.
克罗恩病（CD）的临床表现可能因炎症的部位和强度而有所不同。一些患者可能有非典型症状，这可能会延迟诊断。我们报告了首例与亚临床、复杂性CD相关的慢性荨麻疹病例。尽管在我们的患者中这种关联的病理机制尚不清楚，但该病例表明，对于不明原因的慢性荨麻疹患者，即使没有或只有很少的肠道炎症性疾病的特异性症状，也应适时排查是否可能患有CD。
