Department of Chemistry, National Sun Yat-sen University, Kaohsiung, Taiwan.
Chem Commun (Camb). 2011 Oct 21;47(39):11134-6. doi: 10.1039/c1cc14429d. Epub 2011 Sep 7.
This study describes the development of a simple, sensitive, and selective-detection system for coralyne and polyadenylation reaction based on the fact that coralyne induces a conformational change of the polyadenosine [poly(A)] oligonucleotide through A-coralyne-A coordination, thereby enhancing the fluorescence of SYBR Green I.
本研究描述了一种简单、灵敏和选择性检测珊瑚素和多聚腺苷酸化反应的系统的开发，其基于以下事实：珊瑚素通过 A-珊瑚素-A 配位诱导多聚腺苷酸[poly(A)]寡核苷酸构象变化，从而增强 SYBR Green I 的荧光。
