Division of Nephrology, Department of Internal Medicine, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama, Japan.
Clin Exp Nephrol. 2011 Dec;15(6):942-7. doi: 10.1007/s10157-011-0515-0. Epub 2011 Sep 7.
A 42-year-old female end-stage renal disease (ESRD) patient with reversible posterior leukoencephalopathy syndrome (RPLS) post-transfusion during initiation of hemodialysis is reported. Eleven days after the onset of illness, we diagnosed encephalopathy as a grand mal seizure resulting from diffuse cerebral edema. One reason for the delayed diagnosis was that her symptom, a throbbing headache that occurred during her first dialysis, indicated dialysis disequilibrium syndrome. We must bear in mind that a small amount of transfusion could cause RPLS even during the first dialysis. To our knowledge, this is the first case report on RPLS after blood transfusion in an ESRD patient.
现报道 1 例 42 岁女性终末期肾病（ESRD）患者在开始血液透析时因输血后可逆性后部白质脑病综合征（RPLS）。疾病发作后 11 天，我们诊断脑病为弥漫性脑水肿引起的大发作癫痫。诊断延迟的一个原因是她的症状，即在第一次透析时发生的搏动性头痛，表明透析失衡综合征。我们必须记住，即使在第一次透析时，少量输血也可能导致 RPLS。据我们所知，这是首例 ESRD 患者输血后发生 RPLS 的病例报告。
