Department of Neurosciences, Pediatric Neurosurgery, A. Gemelli Hospital, Rome, Italy.
Neurol Sci. 2011 Dec;32 Suppl 3:S263-5. doi: 10.1007/s10072-011-0700-7.
Chiari type I malformation (CIM) was first described in the late 19th Century. However, it still raises a great interest among the scientific Community because of the increasing number of diagnosed cases, the still unclear pathogenesis and natural history and the different options in the surgical management. The present review aims at analyzing the centenary history of CIM, starting from the first description done by Hans Chiari to the more recent classification, in order to introduce such a complex disease and to show the way followed for its assessment over the time.
Chiari Ⅰ 型畸形(CIM)于 19 世纪末期首次被描述。然而,由于诊断病例的数量不断增加、发病机制和自然病史仍不清楚以及手术治疗的选择不同,它仍然引起了科学界的极大兴趣。本综述旨在分析 CIM 的百年历史,从 Hans Chiari 的首次描述开始,一直到最近的分类,以介绍这种复杂的疾病,并展示随着时间的推移对其评估所遵循的方法。