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UniCarbKB:为糖组学研究整合资源。

UniCarbKB: putting the pieces together for glycomics research.

机构信息

Biomolecular Frontiers Research Centre, Macquarie University, Sydney, NSW, Australia.

出版信息

Proteomics. 2011 Nov;11(21):4117-21. doi: 10.1002/pmic.201100302. Epub 2011 Sep 19.

Abstract

Despite the success of several international initiatives the glycosciences still lack a managed infrastructure that contributes to the advancement of research through the provision of comprehensive structural and experimental glycan data collections. UniCarbKB is an initiative that aims to promote the creation of an online information storage and search platform for glycomics and glycobiology research. The knowledgebase will offer a freely accessible and information-rich resource supported by querying interfaces, annotation technologies and the adoption of common standards to integrate structural, experimental and functional data. The UniCarbKB framework endeavors to support the growth of glycobioinformatics and the dissemination of knowledge through the provision of an open and unified portal to encourage the sharing of data. In order to achieve this, the framework is committed to the development of tools and procedures that support data annotation, and expanding interoperability through cross-referencing of existing databases. Database URL: http://www.unicarbkb.org.

摘要

尽管有几项国际倡议取得了成功,但糖科学仍然缺乏一个管理的基础设施,通过提供全面的结构和实验性聚糖数据集合来促进研究的进展。UniCarbKB 是一项旨在促进创建一个在线信息存储和搜索平台的倡议,用于糖组学和糖生物学研究。该知识库将提供一个免费访问和信息丰富的资源,支持查询接口、注释技术以及采用通用标准来整合结构、实验和功能数据。UniCarbKB 框架努力通过提供一个开放和统一的门户来支持糖生物信息学的发展和知识的传播,以鼓励数据共享。为了实现这一目标,该框架致力于开发支持数据注释的工具和程序,并通过交叉引用现有数据库来扩展互操作性。数据库 URL:http://www.unicarbkb.org。

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