Nicholls D S, Christmas T I, Greig D E
St. John's Hospital for Diseases of the Skin, London, U.K.
J Am Acad Dermatol. 1990 May;22(5 Pt 1):815-9. doi: 10.1016/0190-9622(90)70114-w.
Blister beetle dermatosis is a distinctive vesiculobullous eruption that occurs after contact with three major groups of beetles (Order: Coleoptera). It is caused by a vesicant chemical contained in the body fluids of the beetles. The smallest and least known family is the Oedemeridae. Although there are few references in the medical literature, blister beetle dermatosis caused by oedemerids may be more common and widespread than currently recognized. The best known family is the Meloidae with numerous species worldwide causing blistering. The vesicant chemical in both Oedemeridae and Meloidae is cantharidin. The third group of blister beetles includes species of the genus Paederus (Family: Staphylinidae). The clinicopathologic picture differs because this genus contains a different vesicant agent, pederin. The clinicopathologic features of oedemerid blister beetle dermatosis are described. The world medical and relevant entomologic literature is reviewed.
芫菁皮炎是一种独特的水疱大疱性皮疹，在接触三大类甲虫（鞘翅目）后发生。它由甲虫体液中含有的一种发泡剂化学物质引起。最小且最不为人知的科是拟天牛科。尽管医学文献中提及较少，但拟天牛科引起的芫菁皮炎可能比目前所认识到的更为常见和广泛。最知名的科是芫菁科，全球有众多物种可导致水疱形成。拟天牛科和芫菁科中的发泡剂化学物质均为斑蝥素。第三类芫菁甲虫包括隐翅虫属（隐翅虫科）的物种。临床病理表现有所不同，因为该属含有一种不同的发泡剂——隐翅虫素。本文描述了拟天牛科芫菁皮炎的临床病理特征，并对世界医学及相关昆虫学文献进行了综述。
