Okubo Tetsuyuki, Takahashi Hiroshi, Kaneko Yukihiro, Kurokawa Takanori, Kanai Motoshi
Department of Surgery, Hakodate Medical Hospital, Hakodate, Japan.
Kyobu Geka. 2011 Sep;64(10):951-3.
A 58-year-old female was admitted to our hospital for investigation of serum elevation of carbohydrate antigen (CA 19-9). Computed tomography of the chest revealed a spiculated pulmonary nodule with the longest diameter of 3.7 cm in the right lower lobe. The diagnosis of lung adenocarcinoma was made. The patient underwent right lower lobectomy with lymphnode dissection. Histological examination revealed acinar type adenocarcinoma. The tumor was classified as stage IB with T2aN0M0. Immunohistochemically, the tumor cells stained positively for CA19-9. The serum CA19-9 level returned to a normal level after operation, but increased again with mediastinal lymphnode metastasis and brain metastasis. She died after an operation in 16 months.
一名58岁女性因糖类抗原（CA 19-9）血清水平升高入院我院进行检查。胸部计算机断层扫描显示右下叶有一个最长直径为3.7厘米的毛刺状肺结节。诊断为肺腺癌。患者接受了右下叶切除术及淋巴结清扫术。组织学检查显示为腺泡型腺癌。肿瘤被分类为IB期，T2aN0M0。免疫组织化学检查显示肿瘤细胞CA19-9染色呈阳性。术后血清CA19-9水平恢复正常，但随着纵隔淋巴结转移和脑转移再次升高。她在术后16个月死亡。
