Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra ACT 0200, Australia.
J Org Chem. 2011 Oct 21;76(20):8560-3. doi: 10.1021/jo2016899. Epub 2011 Sep 27.
The structure 3 recently proposed, on the basis of computed NMR chemical shifts, for the natural product nobilisitine A has been synthesized from its C5-epimer (+)-clividine (4). The spectral data derived from compound 3 match those reported for the natural product.
基于计算 NMR 化学位移提出的天然产物诺比利西汀 A 的结构 3 已由其 C5-差向异构体 (+)-可利文定(4)合成。化合物 3 的谱学数据与天然产物报道的数据相符。