Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Epilepsy Res. 2011 Nov;97(1-2):220-4. doi: 10.1016/j.eplepsyres.2011.08.008. Epub 2011 Sep 6.
To evaluate the association between cerebral hypoperfusion and seizure termination, we compared seizure duration in seven patients with syncopal ictal asystole (IA), seven with non-syncopal ictal bradycardia, and ten with non-bradycardic seizures. Mean seizure duration was 34.4±13 s in IA, 67±28.9 s in ictal bradycardia, and 82.1±31.1 in non-bradycardic seizures. These were significantly different (ANOVA, p<0.02). This suggests cerebral hypoxia-ischemia favors seizure termination.
为了评估脑灌注不足与癫痫发作终止之间的关系，我们比较了 7 例晕厥性癫痫发作停搏（IA）、7 例非晕厥性癫痫发作心动过缓及 10 例非心动过缓性癫痫发作患者的癫痫发作持续时间。IA 患者的平均癫痫发作持续时间为 34.4±13 秒，发作性心动过缓患者为 67±28.9 秒，非心动过缓性癫痫发作患者为 82.1±31.1 秒。这些差异具有统计学意义（ANOVA，p<0.02）。这表明脑缺氧缺血有利于癫痫发作终止。
