Vaughan E D, Carey R M, Ayers C R, Peach M J
J Clin Endocrinol Metab. 1979 May;48(5):869-71. doi: 10.1210/jcem-48-5-869.
In two patients with end stage renal disease and dialysis-resistant hypertension, the orally active inhibitor of angiotensin-converting enzyme, captopril (SQ14,225; 2-D-methyl-3-mercaptopropranoyl-L-proline, dramatically lowered blood pressure both before and during dialysis. This agent holds promise as an alternate to bilateral nephrectomy in such patients.