Captopril (SQ 14,225) (D-3-mercapto-2-methylpropranoyl-L-proline): a novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent.

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作者信息

Rubin B, Antonaccio M J, Horovitz Z P

出版信息

Prog Cardiovasc Dis. 1978 Nov-Dec;21(3):183-94. doi: 10.1016/0033-0620(78)90024-5.

DOI:10.1016/0033-0620(78)90024-5

PMID:214818

Abstract

摘要

相似文献

Captopril (SQ 14,225) (D-3-mercapto-2-methylpropranoyl-L-proline): a novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent.

Prog Cardiovasc Dis. 1978 Nov-Dec;21(3):183-94. doi: 10.1016/0033-0620(78)90024-5.

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.SQ 14,225（D-3-巯基-2-甲基丙酰基-L-脯氨酸），一种新型的口服活性血管紧张素I转换酶抑制剂。

J Pharmacol Exp Ther. 1978 Feb;204(2):271-80.

Chronic antihypertensive effects of captopril (SQ 14,225), an orally active angiotensin I-converting enzyme inhibitor, in conscious 2-kidney renal hypertensive rats.

Eur J Pharmacol. 1978 Oct 15;51(4):377-88. doi: 10.1016/0014-2999(78)90429-6.

Antihypertensive action of a novel orally active angiotensin converting enzyme inhibitor altiopril calcium (MC-838) in several hypertensive models of rats: comparison with captopril.新型口服活性血管紧张素转换酶抑制剂阿尔替普利钙（MC - 838）在几种大鼠高血压模型中的降压作用：与卡托普利的比较。

Arch Int Pharmacodyn Ther. 1988 Mar-Apr;292:203-22.

Antihypertensive activity of captopril (SQ 14,225), an orally active inhibitor of angiotensin converting enzyme in conscious two-kidney perinephritic hypertensive dogs.卡托普利（SQ 14,225）对清醒双肾肾周性高血压犬的降压活性，卡托普利是一种口服有效的血管紧张素转换酶抑制剂。

J Pharmacol Exp Ther. 1981 Feb;216(2):225-31.

Acute vasodepressor effect of D-3-mercapto-2-methylpropanoyl-L-proline (SQ 14,225) in the stroke-prone substrain of spontaneously hypertensive rats (SHRSP).D-3-巯基-2-甲基丙酰-L-脯氨酸（SQ 14,225）对易卒中型自发性高血压大鼠（SHRSP）的急性血管减压作用。

Jpn J Pharmacol. 1979 Feb;29(1):133-5. doi: 10.1254/jjp.29.133.

Antihypertensive activity of alacepril, an orally active angiotensin converting enzyme inhibitor, in renal hypertensive rats and dogs.口服活性血管紧张素转换酶抑制剂阿拉普利在肾性高血压大鼠和犬中的降压活性。

Arzneimittelforschung. 1985;35(10):1502-7.

Hemodialysis-resistant hypertension: control with an orally active inhibitor of angiotensin-converting enzyme.

J Clin Endocrinol Metab. 1979 May;48(5):869-71. doi: 10.1210/jcem-48-5-869.

Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.血管紧张素转换酶特异性抑制剂的设计：新型口服活性抗高血压药物

Science. 1977 Apr 22;196(4288):441-4. doi: 10.1126/science.191908.

Inhibitors of the renin-angiotensin system in experimental hypertension, with a note on the measurement of angiotensin I, II and III during infusion of converting-enzyme inhibitor.实验性高血压中肾素-血管紧张素系统抑制剂，以及关于在输注转化酶抑制剂期间测量血管紧张素I、II和III的说明

Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):233S-241S. doi: 10.1111/j.1365-2125.1979.tb04695.x.

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A comparison of the ability of two angiotensin II receptor blocking drugs, 1-Sar; 8-Ala angiotensin II and 1-Sar, 8-Ile angiotensin II, to modify the regulation of glomerular filtration rate in the cat.比较两种血管紧张素II受体阻断药物，即1-肌氨酸；8-丙氨酸血管紧张素II和1-肌氨酸，8-异亮氨酸血管紧张素II对猫肾小球滤过率调节的影响。

Br J Pharmacol. 1980;71(2):499-506. doi: 10.1111/j.1476-5381.1980.tb10963.x.

Captopril as treatment for patients with pulmonary hypertension. Problem of variability in assessing chronic drug treatment.卡托普利治疗肺动脉高压患者。评估慢性药物治疗的变异性问题。

Br Heart J. 1982 Sep;48(3):272-7. doi: 10.1136/hrt.48.3.272.

The renin-angiotensin system in drinking and cardiovascular responses to isoprenaline in the rat.大鼠饮用及对异丙肾上腺素心血管反应中的肾素-血管紧张素系统

J Physiol. 1981 Jul;316:357-67. doi: 10.1113/jphysiol.1981.sp013793.

The involvement of arachidonic acid metabolism in the control of renin release.花生四烯酸代谢在肾素释放调控中的作用。

J Endocrinol Invest. 1980 Apr-Jun;3(2):193-201. doi: 10.1007/BF03348251.

Effects of an angiotensin-converting enzyme inhibitor (captopril) on blood pressure in anephric subjects.血管紧张素转换酶抑制剂（卡托普利）对无肾受试者血压的影响。

Br Med J. 1980 Feb 2;280(6210):288-90. doi: 10.1136/bmj.280.6210.288.

Racial differences in response to low-dose captopril are abolished by the addition of hydrochlorothiazide.加用氢氯噻嗪后，对小剂量卡托普利反应的种族差异消失。

Br J Clin Pharmacol. 1982;14 Suppl 2(Suppl 2):97S-101S.

The effect of kinins on paw oedema and uterus in rats.激肽对大鼠爪部水肿和子宫的影响。

Naunyn Schmiedebergs Arch Pharmacol. 1984 Dec;328(2):202-6. doi: 10.1007/BF00512073.

Increased or decreased thirst caused by inhibition of angiotensin-converting enzyme in the rat.大鼠体内血管紧张素转换酶受抑制导致口渴增加或减少。

J Physiol. 1984 Mar;348:573-88. doi: 10.1113/jphysiol.1984.sp015126.

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