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成人前交叉韧带断裂:髌腱自体移植与腘绳肌腱自体移植的比较

Patellar tendon versus hamstring tendon autograft for anterior cruciate ligament rupture in adults.

作者信息

Mohtadi Nicholas Gh, Chan Denise S, Dainty Katie N, Whelan Daniel B

机构信息

Orthopaedic Surgery, University of Calgary, Sport Medicine Centre, 2500 University Drive NW, Calgary, Alberta, Canada, T2N 1N4.

出版信息

Cochrane Database Syst Rev. 2011 Sep 7;2011(9):CD005960. doi: 10.1002/14651858.CD005960.pub2.

Abstract

BACKGROUND

Reconstruction of the anterior cruciate ligament (ACL) commonly involves patellar tendon (PT) or hamstring tendon(s) (HT) autografts. There is no consensus with respect to the choice between these two grafts in ACL surgery.

OBJECTIVES

This review compared the outcomes of ACL reconstruction using PT versus HT autografts in ACL deficient patients.

SEARCH STRATEGY

We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (April 2008), the Cochrane Central Register of Controlled Trials (2008, Issue 2), MEDLINE (1966 to April 10 2008), EMBASE (1980 to April 10 2008), conference proceedings and reference lists. No language restrictions were applied.

SELECTION CRITERIA

Randomized and quasi-randomized controlled trials comparing outcomes (minimum two year follow-up) following ACL reconstruction using either PT or HT autografts in skeletally mature adults, irrespective of the number of bundles, fixation method or incision technique.

DATA COLLECTION AND ANALYSIS

After independent study selection, the four authors independently assessed trial quality and risk of bias, and extracted data using pre-developed forms. Trial authors were contacted for additional data and information. Risk ratios with 95% confidence intervals were calculated for dichotomous outcomes, and mean differences and 95% confidence intervals for continuous outcomes.

MAIN RESULTS

Nineteen trials providing outcome data for 1597 young to middle-aged adults were included. Many trials were at high risk of bias reflecting inadequate methods of randomization, lack of blinding and incomplete assessment of outcome.Pooled data for primary outcomes, reported in a minority of trials, showed no statistically significant differences between the two graft choices for functional assessment (single leg hop test), return to activity, Tegner and Lysholm scores, and subjective measures of outcome. There were also no differences found between the two interventions for re-rupture or International Knee Documentation Committee scores. There were inadequate long-term results, such as to assess the development of osteoarthritis.All tests (instrumental, Lachman, pivot shift) for static stability consistently showed that PT reconstruction resulted in a more statically stable knee compared with HT reconstruction. Conversely, patients experienced more anterior knee problems, especially with kneeling, after PT reconstruction. PT reconstructions resulted in a statistically significant loss of extension range of motion and a trend towards loss of knee extension strength. HT reconstructions demonstrated a trend towards loss of flexion range of motion and a statistically significant loss of knee flexion strength. The clinical importance of the above range of motion losses is unclear.

AUTHORS' CONCLUSIONS: There is insufficient evidence to draw conclusions on differences between the two grafts for long-term functional outcome. While PT reconstructions are more likely to result in statically stable knees, they are also associated with more anterior knee problems.

摘要

背景

前交叉韧带(ACL)重建通常采用髌腱(PT)或腘绳肌腱(HT)自体移植。在ACL手术中,对于这两种移植物的选择尚无共识。

目的

本综述比较了ACL缺损患者使用PT与HT自体移植物进行ACL重建的效果。

检索策略

我们检索了Cochrane骨、关节和肌肉创伤小组专业注册库(2008年4月)、Cochrane对照试验中心注册库(2008年第2期)、MEDLINE(1966年至2008年4月10日)、EMBASE(1980年至2008年4月10日)、会议论文集和参考文献列表。未设语言限制。

选择标准

比较骨骼成熟成年人使用PT或HT自体移植物进行ACL重建后效果(至少两年随访)的随机和半随机对照试验,无论束的数量、固定方法或切口技术如何。

数据收集与分析

在独立进行研究选择后,四位作者独立评估试验质量和偏倚风险,并使用预先制定的表格提取数据。与试验作者联系以获取更多数据和信息。对二分结局计算风险比及95%置信区间,对连续结局计算均值差及95%置信区间。

主要结果

纳入了19项为1597名年轻至中年成年人提供结局数据的试验。许多试验存在较高偏倚风险,反映出随机化方法不充分、缺乏盲法以及结局评估不完整。少数试验报告的主要结局汇总数据显示,在功能评估(单腿跳测试)、恢复活动情况、Tegner和Lysholm评分以及结局主观指标方面,两种移植物选择之间无统计学显著差异。两种干预措施在再断裂或国际膝关节文献委员会评分方面也未发现差异。长期结果不足,无法评估骨关节炎的发展情况。所有静态稳定性测试(器械检查、Lachman试验、轴移试验)一致表明,与HT重建相比,PT重建使膝关节在静态上更稳定。相反,PT重建后患者出现更多的膝前问题,尤其是跪姿时。PT重建导致伸展活动范围有统计学显著损失,且有膝关节伸展力量损失的趋势。HT重建显示有屈曲活动范围损失的趋势,且膝关节屈曲力量有统计学显著损失。上述活动范围损失的临床重要性尚不清楚。

作者结论

没有足够证据就两种移植物在长期功能结局上的差异得出结论。虽然PT重建更有可能使膝关节在静态上稳定,但也会带来更多的膝前问题。

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