DNA 的热力学：负载下热稳定性的理论。
Thermomechanics of DNA: theory of thermal stability under load.
机构信息
Theoretical Division, Los Alamos National Laboratory, New Mexico 87545, USA.
出版信息
Phys Rev Lett. 2011 Aug 5;107(6):068102. doi: 10.1103/PhysRevLett.107.068102. Epub 2011 Aug 2.
Abstract
A theory for thermomechanical behavior of homogeneous DNA at thermal equilibrium predicts critical temperatures for denaturation under torque and stretch, phase diagrams for stable B-DNA, supercoiling, optimally stable torque, and the overstretching transition as force-induced DNA melting. Agreement with available single molecule manipulation experiments is excellent.
摘要
一个关于热平衡状态下均一 DNA 的热力学行为的理论，预测了在扭矩和拉伸下变性的临界温度、稳定 B-DNA 的相图、超螺旋、最优稳定扭矩，以及力诱导 DNA 熔解的超拉伸转变。与现有的单分子操纵实验吻合得极好。
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