Department of Dentistry, Potiguar University, Natal, RN, Brazil.
Angle Orthod. 2012 Mar;82(2):242-6. doi: 10.2319/060711-373.1. Epub 2011 Sep 8.
To evaluate the effects of unilateral and bilateral premature loss of posterior occlusal support on mandibular bone dimensions in growing rats.
Thirty female Wistar rats (5 weeks old) were randomized into three groups: control, unilateral mandibular molar teeth extraction, and bilateral mandibular molar teeth extraction. After 8 weeks, animals were sacrificed and acrylic rapid-prototyped templates of the mandibles were constructed. Mandibular length, ramus height, intercondylar distance, and body weight were measured and analyzed by one-way analysis of variance (Tukey test as post hoc test; α = .05).
Mandibular length and intercondylar distance were significantly shorter in experimental animals, while no difference was observed for ramus height and body weight.
Unilateral and bilateral premature loss of posterior occlusal support in growing rats results in a smaller mandible at skeletal maturity.
评估单侧和双侧后牙早失对生长大鼠下颌骨尺寸的影响。
30 只雌性 Wistar 大鼠（5 周龄）随机分为三组：对照组、单侧下颌磨牙拔除组和双侧下颌磨牙拔除组。8 周后，处死动物并制作下颌骨的丙烯酸快速原型模板。通过单因素方差分析（Tukey 检验作为事后检验；α=0.05）测量和分析下颌长度、髁突高度、髁间距离和体重。
实验组下颌长度和髁间距离明显缩短，而髁突高度和体重无差异。
生长大鼠单侧和双侧后牙早失导致下颌骨在骨骼成熟时更小。
