大鼠移动 2 颗磨牙对下颌髁突软骨的影响。

Mandibular condylar cartilage response to moving 2 molars in rats.

机构信息

Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi'an, China.

出版信息

Am J Orthod Dentofacial Orthop. 2010 Apr;137(4):460.e1-8; discussion 460-1. doi: 10.1016/j.ajodo.2009.09.018.

DOI:10.1016/j.ajodo.2009.09.018

PMID:20362904

Abstract

INTRODUCTION

The purpose of this study was to investigate the responses of mandibular condylar cartilage to moving 2 molars in different combinations.

METHODS

Rats were assigned to male and female control and experimental groups (each, n = 5). Elastic rubber bands were used to move medially the maxillary left and the mandibular right first molars in experimental group I. The same method was used to distally move the maxillary left and the mandibular right third molars, 2 mandibular third molars, and 2 maxillary third molars in experimental groups II, III, and IV, respectively. At the end of the eighth week, all condyles were examined histologically. The areas of histologic change as a percentage of total cartilage area were compared by using the Mann-Whitney U test.

RESULTS

Cartilage degenerative remodeling was observed in experimental groups II, III, and IV. The percentage areas of degenerative remodeling were higher in female experimental groups II and III than in the female control group, and in female experimental group II than in female experimental group IV and male experimental group II (all, P <0.05).

CONCLUSIONS

The mandibular condylar cartilage of female rats responded variously to different combinations of molar movement; the most obvious remodeling was observed in groups in which the maxillary left and mandibular right third molars were moved.

摘要

简介

本研究旨在探讨不同磨牙移动组合对下颌髁突软骨的影响。

方法

将大鼠分为雄性和雌性对照组和实验组（每组 n = 5）。实验组 I 通过弹性橡皮圈将左侧上颌第一磨牙和右侧下颌第一磨牙向内侧移动。实验组 II、III 和 IV 分别采用相同的方法将左侧上颌第三磨牙和右侧下颌第三磨牙、2 个下颌第三磨牙和 2 个上颌第三磨牙向远中移动。第 8 周末，所有髁突均行组织学检查。采用曼-惠特尼 U 检验比较组织学变化面积占软骨总面积的百分比。