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[细胞因子在实现骨髓输注、孵育及再植入程序对受辐照小鼠的修复作用中的意义]

[The significance of the cellular factor in realizing the restorative effect of the procedure of bone marrow exfusion, incubation and reimplantation in irradiated mice].

作者信息

Zernichenko A N, Limarenko V N, Rozhdestvenskiĭ L M

出版信息

Radiobiologiia. 1990 Mar-Apr;30(2):203-6.

PMID:2190261
Abstract

In experiments with F1 (CBA X C57Bl) mice irradiated with doses of 6.5 to 8.5 Gy the evidence was obtained for the important role of the reimplanted cells in a complete realization of the reparative effect of exfusion, incubation and reimplantation of bone marrow. The increase in radiation dose was accompanied by a tendency towards the decrease in the efficacy of the procedure, and, perhaps, by changes in the ratio of roots of haemopoietic stem cell differentiation.

摘要

在用6.5至8.5 Gy剂量照射的F1(CBA×C57Bl)小鼠实验中,获得的证据表明,重新植入的细胞在完全实现骨髓外渗、孵育和重新植入的修复作用中起重要作用。辐射剂量的增加伴随着该程序功效降低的趋势,并且可能伴随着造血干细胞分化根比例的变化。

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