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2000-2009 年新西兰国家眼库研究:供体角膜组织分布趋势和角膜移植适应证。

Trends in the distribution of donor corneal tissue and indications for corneal transplantation: the New Zealand National Eye Bank Study 2000-2009.

机构信息

New Zealand National Eye Bank, and Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

出版信息

Clin Exp Ophthalmol. 2012 Mar;40(2):141-7. doi: 10.1111/j.1442-9071.2011.02681.x. Epub 2011 Nov 4.

Abstract

BACKGROUND

To investigate the indications for corneal transplantation and the distribution of donor corneal tissue in New Zealand.

DESIGN

Analysis of the prospective database of the New Zealand National Eye Bank.

PARTICIPANTS

A total of 2205 corneal transplants were assessed.

METHODS

New Zealand National Eye Bank records were analysed for the decade 2000-2009.

MAIN OUTCOME MEASURES

Variables analysed included donor corneal tissue distribution (including public and private sectors), indications for transplantation, donor corneal tissue recipient demographics (age and gender) and corneal transplantation type.

RESULTS

An average of 220 corneal transplants were performed each year over the 10-year period (n=2205). The median recipient age was 45years (range 3 to 102years) and 54.0% of recipients were male. In total 71.8% of transplants were performed in the public health sector. Surgeons in the Auckland metropolitan area performed 47.2% of all corneal transplants. The most common indications for corneal transplantation were: keratoconus (41.1%), repeat transplant (17.0%), aphakic/pseudophakic bullous keratopathy (13.9%), corneal dystrophy (10.7%), keratitis (7.9%) and trauma (3.7%). Overall, penetrating keratoplasty accounted for 90.7% of all corneal transplants, however, during the latter half of the study there was a progressive shift in transplantation type, with deep anterior lamellar keratoplasty and Descemet's stripping endothelial keratoplasty combined accounting for 32.3% of all transplants in the final year of the study period.

CONCLUSIONS

This New Zealand National Eye Bank study provides valuable data regarding the indications for corneal transplantation, transplant recipient demographics and changes in transplantation type in New Zealand over the past decade.

摘要

背景

调查新西兰角膜移植的适应证和供体角膜组织的分布情况。

设计

新西兰国家眼库前瞻性数据库分析。

参与者

共评估了 2205 例角膜移植。

方法

分析 2000-2009 年新西兰国家眼库的记录。

主要观察指标

分析的变量包括供体角膜组织的分布(包括公共和私人部门)、移植的适应证、供体角膜组织受者的人口统计学特征(年龄和性别)和角膜移植类型。

结果

在 10 年期间,平均每年进行 220 例角膜移植(n=2205)。中位受者年龄为 45 岁(范围 3-102 岁),54.0%为男性。总共 71.8%的移植在公共卫生部门进行。奥克兰大都市区的外科医生进行了所有角膜移植的 47.2%。角膜移植的最常见适应证为:圆锥角膜(41.1%)、重复移植(17.0%)、无晶状体/人工晶状体后大泡性角膜病变(13.9%)、角膜营养不良(10.7%)、角膜炎(7.9%)和外伤(3.7%)。总体而言,穿透性角膜移植占所有角膜移植的 90.7%,但在研究后期,移植类型逐渐发生变化,深层前板层角膜移植和 Descemet 撕囊内皮角膜移植联合占研究最后一年所有移植的 32.3%。

结论

这项新西兰国家眼库研究提供了有关过去十年新西兰角膜移植适应证、移植受者人口统计学特征和移植类型变化的有价值数据。

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