Department of Ophthalmology, National Eye Bank, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Department of Ophthalmology, Ramayamma International Eye Bank, LVPEI, Hyderabad, Telangana, India.
Indian J Ophthalmol. 2019 Jul;67(7):1056-1059. doi: 10.4103/ijo.IJO_1551_18.
To study the trends in collection, storage and utilization of donor corneas in eye banks in India.
The data was collected from 12 eye banks in India that collected more than 1000 corneas per year. The retrospective analysis of the parameters like characteristics of the donor and the host, storage media used, number of eyes collected, number of eyes utilized, causes of non-utilization of the tissue and the procedures performed was done.
A total of 20,564 eyes were collected by the 12 eye banks during the year 2013-2014. Voluntary eye donation (VED), and hospital cornea retrieval program (HCRP) contributed to 59.6% and 40.4% of tissue procurement respectively. Whole globe enucleation (52.3%) was more commonly performed as compared to in-situ excision of the donor corneas. The most commonly used storage media at all eye banks was McCarey-Kaufman (MK) media (83.3%). The utilization rate of the donor eyes was 50.5%. The most frequent indication for corneal transplantation was infection (active infection - 33.13%, healed infection - 10.78%) followed by Pseudophakic bullous keratopathy (PBK) (13.57%). Full thickness keratoplasty (optical penetrating keratoplasty - 47.23%, therapeutic penetrating keratoplasty - 31.74%) was performed most often followed by endothelial keratoplasty (12.41%) in the developing country.
VED still contributes to majority of the donor tissue retrieval in India. The majority of the eye banks still utilize whole globe enucleation technique and store tissues in MK media. Trends from previous years showed a change towards HCRP, in-situ excision technique and preservation in the long-term storage media.
研究印度眼库中供体角膜采集、储存和利用的趋势。
从每年收集 1000 多只角膜的 12 家印度眼库中收集数据。对供体和受者的特征、使用的储存介质、收集的眼睛数量、利用的眼睛数量、组织未利用的原因以及所进行的程序等参数进行回顾性分析。
2013-2014 年，12 家眼库共采集 20564 只眼睛。自愿性眼捐献（VED）和医院角膜检索计划（HCRP）分别占组织采集的 59.6%和 40.4%。眼球全切除术（52.3%）比原位切除供体角膜更为常见。所有眼库最常用的储存介质均为 McCarey-Kaufman（MK）介质（83.3%）。供体眼的利用率为 50.5%。角膜移植的最常见指征是感染（活动性感染-33.13%，愈合感染-10.78%），其次是假性囊泡性角膜病变（PBK）（13.57%）。在这个发展中国家，最常进行的是全层角膜移植术（光学穿透性角膜移植术-47.23%，治疗性穿透性角膜移植术-31.74%），其次是内皮角膜移植术（12.41%）。
VED 仍然是印度大多数供体组织获取的来源。大多数眼库仍然使用眼球全切除术技术，以及在 MK 培养基中储存组织。从过去几年的趋势来看，眼库更倾向于使用 HCRP、原位切除技术和长期储存介质。
