Huynh Christophe, Guilé Jean-Marc, Godbout Roger
Hôpital Rivière-des-Prairies, clinique des troubles de l'humeur, 7070, boulevard Perras, Montréal, Québec, H1E 1A4 Canada.
Presse Med. 2012 Feb;41(2):e63-75. doi: 10.1016/j.lpm.2011.06.019. Epub 2011 Sep 7.
Borderline personality disorder (BPD) represents 2% of the general population, 10% of outpatient psychiatry facilities, 20% of inpatients and nearly 41% of patients seen in Emergency Room for attempted suicide. Also, 10% complete suicide and 64-66% have comorbid substance dependence. In addition, several studies report sleep subjective complaints in patients with BPD, and research has explored objective sleep disturbances.
To examine the results of previous studies in polysomnography in BPD to better characterize the objective sleep disturbances in this population.
A review of the literature on MedLine and PsycINFO using the term "borderline personality disorder", "sleep" and "polysomnography" allowed the review of 15 original articles on sleep assessed by PSG in subjects adults with BPD, published between 1980 and may 2010.
Compared with healthy subjects, a decreased onset delay of rapid eye movements (REM) sleep and an increased REM density have been observed in BPD. In addition BPD shares with major depression the following disturbances: increase in onset latency, decreased total sleep time and efficiency.
Differences between studies regarding sex, age, mood state at the time of the study and psychiatric comorbidity influence the results, which explains the disparity in findings.
There are objective disturbances associated with BPD according to polysomnographic studies.
边缘型人格障碍(BPD)在普通人群中的占比为2%,在门诊精神科患者中占10%,住院患者中占20%,而在因自杀未遂前往急诊室就诊的患者中占近41%。此外,10%的患者完成自杀,64 - 66%的患者合并物质依赖。另外,多项研究报告了BPD患者的睡眠主观主诉,并且已有研究探讨了客观睡眠障碍。
检查先前关于BPD患者多导睡眠图的研究结果,以更好地描述该人群的客观睡眠障碍特征。
通过在MedLine和PsycINFO上检索文献,使用“边缘型人格障碍”“睡眠”和“多导睡眠图”等术语,对1980年至2010年5月期间发表的15篇关于成年BPD患者通过多导睡眠图评估睡眠的原始文章进行了综述。
与健康受试者相比,BPD患者观察到快速眼动(REM)睡眠起始延迟减少以及REM密度增加。此外,BPD与重度抑郁症存在以下共同的睡眠障碍:入睡潜伏期延长、总睡眠时间和睡眠效率降低。
研究在性别、年龄、研究时的情绪状态以及精神共病方面存在差异,影响了研究结果,这解释了研究结果的不一致性。
根据多导睡眠图研究,BPD存在客观睡眠障碍。