• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Maillard compounds as a cause of aging].

作者信息

Azevedo M S

机构信息

Instituto de Química Fisiológica, Faculdade de Medicina, Lisboa.

出版信息

Acta Med Port. 1990 Mar-Apr;3(2):126-8.

PMID:2190445
Abstract

Several theories have been presented to explain the mechanism of aging. Among those theories, two are supported by strong reasons: the generation of oxygen radicals and nonenzymatic glycosylation of proteins. Oxygen and glucose are essential for the central nervous system (and practically for all tissues) and at the same time they are the main cause of aging. Through our demonstration that Maillard compounds generate oxygen free radicals, both theories may be united in one.

摘要

相似文献

1
[Maillard compounds as a cause of aging].
Acta Med Port. 1990 Mar-Apr;3(2):126-8.
2
Native protein glycoxidation and aging.天然蛋白质糖基化氧化与衰老。
J Nutr Health Aging. 2003;7(4):263-6.
3
[Aging and free radicals].[衰老与自由基]
Acta Med Port. 1992 Feb;5(2):87-90.
4
[Epigenetic mechanisms of aging: relations between Maillard reactions and radical generation].
C R Seances Soc Biol Fil. 1997;191(2):247-52.
5
Maillard reaction products in tissue proteins: new products and new perspectives.组织蛋白质中的美拉德反应产物:新产品与新视角。
Amino Acids. 2003 Dec;25(3-4):275-81. doi: 10.1007/s00726-003-0017-9. Epub 2003 Jul 29.
6
An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions.一个新出现的假说:自由基与美拉德反应对衰老的协同诱导作用。
J Gerontol. 1992 Jul;47(4):B107-14. doi: 10.1093/geronj/47.4.b107.
7
Toward a Maillard reaction theory of aging.迈向衰老的美拉德反应理论。
Prog Clin Biol Res. 1989;304:1-22.
8
[Nonenzymatic glycosylation (the Maillard reaction) in the body].[体内的非酶糖基化(美拉德反应)]
Vopr Pitan. 1988 Sep-Oct(5):4-9.
9
The Maillard reaction and its consequences for a living body.美拉德反应及其对生物体的影响。
Ann Univ Mariae Curie Sklodowska Med. 2003;58(2):159-62.
10
Peroxyl radicals are essential reagents in the oxidation steps of the Maillard reaction leading to generation of advanced glycation end products.过氧自由基是美拉德反应氧化步骤中的关键试剂,该反应会导致晚期糖基化终产物的生成。
Ann N Y Acad Sci. 2008 Apr;1126:128-33. doi: 10.1196/annals.1433.031.